4-Methylumbelliferyl-Beta-D-Glucopyranoside(CAS 18997-57-4)
| Purity | Grade | Package | Stock | Price | Quantity |
| 99% | RG | 1G | In Stock | 10 USD
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Your region is eligible for ordering. Available NMR Spectrum
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Applications of 18997-57-4
| Industry | Application | Process |
|---|---|---|
| Biomedical Research | Reagent for detecting β-glucuronidase activity | Enzymatic hydrolysis: In a pH 4.5–5.0 buffer system, the substrate is specifically hydrolyzed by β-glucuronidase to release highly fluorescent 4-methylumbelliferone (4-MU), enabling quantitative measurement of enzyme activity via fluorometric spectrophotometry (excitation at 365 nm, emission at 445 nm) |
| Clinical Diagnostics | Detection of β-glucuronidase activity in urine, tissue homogenates, or cell lysates for auxiliary screening of lysosomal storage disorders (e.g., Sanfilippo syndrome type B) | After sample pretreatment, the substrate is added and incubated at 37 °C for 30–60 min; the reaction is then terminated and fluorescence intensity measured, with enzyme activity calculated (nmol 4-MU/min/mg protein) against a standard curve |
| Microbiology | Rapid identification of Gram-negative bacteria such as Escherichia coli (some strains express β-glucuronidase) | The substrate is incorporated into selective chromogenic media (e.g., MacConkey agar or CHROMagar); positive colonies hydrolyze the substrate to produce blue fluorescence, enabling direct identification under 365 nm UV light |
| Drug Metabolism Studies | Evaluation of enzymatic stability of drug-glucuronide conjugates and kinetic profiling of coordinated metabolism by UGT and β-glucuronidase | Used as an internal standard or competitive substrate in in vitro hepatic microsomal or recombinant enzyme systems to monitor hydrolysis rate and correct for interference from endogenous β-glucuronidase |
Physical and chemical properties of 18997-57-4
Acidity coefficient |
12.73±0.70(Predicted) |
|---|---|
Boiling Point |
626.9±55.0 °C at 760 mmHg |
BRN |
94672 |
Density |
1.5±0.1 g/cm3 |
Exact Mass |
338.100159 |
Flash Point |
233.9±25.0 °C |
Index of Refraction |
1.641 |
LogP |
-0.46 |
Melting Point |
258-263ºC (dec.) |
Molecular Formula |
C16H18O8 |
Molecular Weight |
338.309 |
PSA |
129.59000 |
Storage condition |
2-8°C |
Vapour Pressure |
0.0±1.9 mmHg at 25°C |
Water Solubility |
Soluble in DMF or water |
λmax |
320nm(Buffer)(lit.) |
Spectrums of 18997-57-4
1.The NMR spectrum displayed on the page is a pre-sale reference spectrum and may differ from that of the actual received batch.
2.The accompanying documentation will include the NMR spectrum and purity analysis data for the shipped batch.
Retrosynthesis analysis of 18997-57-4
Cas:67909-25-5
Cas:133-89-1
Cas:90-33-5
Cas:63700-19-6
Q&A for CAS 18997-57-4
1. How can I verify product quality?
Every batch of our Chemical Reagents is tested to meet ISO 9001 standards. We provide COA & NMR & SDS Provided with each shipment. Batch COA available for verification, and third-party retesting is supported. A full refund is offered if our data is incorrect.
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If your Lab Grade Chemical Reagents do not match the Batch COA available, we will issue a replacement or a full refund upon verification.
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Hazardous products are labeled and packaged following international regulations. We provide SDS Provided with all hazardous shipments to ensure safe and compliant transport.
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Yes, samples are available for selected Lab Grade products. Please submit a request to confirm availability and specifications.
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9. Can you customize purity or packaging?
Yes. We support customization of Lab Grade purity, packaging size, and special testing requirements. Share your needs and we’ll provide a tailored solution.
10. Is the COA consistent with the shipped batch?
Yes. Batch COA available matches the actual shipment. COAs shown online are for reference or from previous batches.
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Yes. We offer Lab Supplier services for stable batch consistency, pricing agreements, and safety stock for long-term customers to ensure uninterrupted supply.
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Download SDS of 18997-57-4
Pictograms |
 |
|---|---|
Signal Word |
Warning |
Hazard Statements |
H302 Harmful if swallowed H315 Causes skin irritation H319 Causes serious eye irritation H335 May cause respiratory irritation |
Safety Data Sheet |
Download COA of 18997-57-4
Operate under the ISO 9001 system
