structure of 190448-57-8

(2S,3S,4S,5R,6S)-6-(4-((2S,3R)-1-(4-Fluorophenyl)-3-((S)-3-(4-Fluorophenyl)-3-Hydroxypropyl)-4-Oxoazetidin-2-Yl)Phenoxy)-3,4,5-Trihydroxytetrahydro-2H-Pyran-2-Carboxylic Acid(CAS 190448-57-8)

CAS No.: 190448-57-8 Brand: MolBest
M. Ft.: C30H29F2NO9 Cat. No: G9734669
M. Wt.: 585.55 MDL: No record
Storage: Store in a cool,dry area. Use: For laboratory research use only
Purity Grade Package Stock Price Quantity
98%
Documents:COASDS
RG 1MG In Stock 169 USD
98%
Documents:COASDS
RG 5MG In Stock 505 USD
98%
Documents:COASDS
RG 25MG In Stock 1718 USD
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Applications of 190448-57-8

Ezetimibe-glucuronide's primary application lies in its role as an active metabolite in lipid-lowering therapies. It is utilized in managing hypercholesterolemia, often in combination with statins to enhance cholesterol-lowering effects without significant drug-drug interactions. The compound's pharmacokinetic properties make it suitable for once-daily dosing regimens, contributing to patient adherence.

Physical and chemical properties of 190448-57-8

Exact Mass

585.18100

Index of Refraction

1.65

LogP

2.51870

Melting Point

140-150ºC

Molecular Formula

C30H29F2NO9

Molecular Weight

585.54900

PSA

156.99000

Solubility

DMSO (Slightly), Methanol (Slightly)

Stability

Hygroscopic

Storage condition

-20°C Freezer

Retrosynthesis analysis of 190448-57-8

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Operate under the ISO 9001 system