Pomalidomide

Pomalidomide is primarily used in oncology for:

• Treating relapsed and refractory multiple myeloma in combination with dexamethasone.
• Potential applications in other hematological malignancies and solid tumors are being explored due to its immunomodulatory effects.

Research is ongoing into its use as a therapeutic agent for conditions such as autoimmune diseases and inflammatory disorders due to its ability to modulate immune responses.

Pomalidomide exhibits significant biological activity, primarily through its immunomodulatory effects. It has been shown to:

• Induce apoptosis in multiple myeloma cells.
• Enhance T-cell activation and proliferation.
• Inhibit angiogenesis, thereby reducing tumor growth.
• Modulate immune responses by affecting cytokine production and immune cell trafficking.

The compound's activity is largely mediated through its interaction with cereblon, a protein that plays a crucial role in the drug's mechanism of action against cancer cells.

Please email your required order quantity and detailed technical specifications to sales@.
Our sales team will promptly prepare an accurate quotation for your bulk order and provide a comprehensive pricing proposal.

All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.