structure of 19293-60-8

(1-Methyl-1H-Indol-3-yl)-Methylamine

CAS No.: 19293-60-8 Brand: MolBest
M. Ft.: C10H12N2 Cat. No: G6704192
M. Wt.: 160.22 MDL: No record
Storage: 2-8°C
Purity Grade Package Stock Price Quantity
99% RG 100MG In Stock 9 USD
99% RG 1G In Stock 38 USD
99% RG 5G In Stock 150 USD
99% RG 25G In Stock 543 USD
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Applications of 19293-60-8

(1-methyl-1H-indol-3-yl)methanamine has several potential applications:

  • Pharmaceutical Development: Due to its antiproliferative properties, it is being investigated as a lead compound for developing new anticancer agents.
  • Chemical Research: It serves as a building block in organic synthesis for creating more complex indole-based compounds with varied biological activities.
  • Biochemical Studies: Its derivatives are used in studies exploring tubulin dynamics and cancer cell biology.

Biological Activity of 19293-60-8

Research has indicated that (1-methyl-1H-indol-3-yl)methanamine and its derivatives exhibit significant biological activities. Notably, studies have shown that certain analogues possess potent antiproliferative effects against various cancer cell lines, including HeLa, MCF-7, and HT-29. For instance, one derivative demonstrated an IC50 value of 0.34 μM against MCF-7 cells, indicating strong inhibitory activity on cell proliferation. Mechanistic studies suggest that these compounds may induce apoptosis and inhibit tubulin polymerization, similar to the action of colchicine.

NMR spectrum of 19293-60-8

Physical sample testing spectrum (NMR) of 19293-60-8

Safety Information of 19293-60-8

Pictograms

Signal Word

Danger

Hazard Statements

H315 Causes skin irritation
H318 Causes serious eye damage
H319 Causes serious eye irritation
H335 May cause respiratory irritation

Safety Data Sheet

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Purchase Instructions of 19293-60-8

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