4-Aminopyridazine
| Purity | Grade | Package | Stock | Price | Quantity |
|---|---|---|---|---|---|
| 98% | RG | 250MG | In Stock | 3 USD | |
| 98% | RG | 1G | In Stock | 6 USD | |
| 98% | RG | 5G | In Stock | 26 USD | |
| 98% | RG | 100G | In Stock | 682 USD | |
| 98% | RG | 500G | In Stock | 3273 USD | |
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Applications of 20744-39-2
4-Aminopyridazine has diverse applications:
- Pharmacological Research: It serves as a critical tool in studying potassium channel conductance and neuronal excitability.
- Clinical Use: The compound is clinically used under the trade name Ampyra (Fampridine) for improving walking in patients with multiple sclerosis. It has shown efficacy in enhancing motor function in spinal cord injury patients as well .
- Toxicology Studies: Its convulsant properties make it valuable for investigating seizure mechanisms and testing potential antiseizure drugs .
Biological Activity of 20744-39-2
4-Aminopyridazine exhibits significant biological activity:
- Potassium Channel Blocker: It selectively blocks voltage-gated potassium channels (Kv1 family), which prolongs action potentials and increases neurotransmitter release at neuromuscular junctions. This mechanism is particularly beneficial in treating conditions like multiple sclerosis and Lambert-Eaton myasthenic syndrome .
- Convulsant Properties: The compound is known to induce seizures in animal models, making it a useful tool for studying antiseizure agents .
- Calcium Channel Activation: Interestingly, 4-Aminopyridazine has been shown to activate calcium channels, enhancing synaptic and neuromuscular function .
NMR spectrum of 20744-39-2
Safety Information of 20744-39-2
Download COA of 20744-39-2
Bulk Packaging Price Explanation of 20744-39-2
Please email your required order quantity and detailed technical specifications to sales@.
Our sales team will promptly prepare an accurate quotation for your bulk order and provide a comprehensive pricing proposal.
Purchase Instructions of 20744-39-2
All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.
These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.
Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.
New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.
