structure of 209995-38-0

2,4,5-Trifluorophenylacetic Acid

CAS No.: 209995-38-0 Brand: MolBest
M. Ft.: C8H5F3O2 Cat. No: G9187720
M. Wt.: 190.12 MDL: MFCD00082479
Storage: Store in a cool,dry area.
Purity Grade Package Stock Price Quantity
98% RG 1G In Stock 3 USD
98% RG 500G In Stock 38 USD
98% RG 2.5KG In Stock 292 USD
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Applications of 209995-38-0

The primary application of 2,4,5-trifluorophenylacetic acid lies in pharmaceutical synthesis. It is notably used in:

  • Synthesis of Sitagliptin: An essential drug for managing type 2 diabetes.
  • Development of Kinase Inhibitors: Used in creating inhibitors for epidermal growth factor receptor (EGFR) and ErbB-2 kinases.
  • Research: Investigated for potential roles in other therapeutic areas due to its unique chemical structure.

Biological Activity of 209995-38-0

The primary biological activity associated with 2,4,5-trifluorophenylacetic acid is its role as a precursor in the synthesis of Sitagliptin, a dipeptidyl peptidase-4 inhibitor used to treat type 2 diabetes. Sitagliptin enhances insulin secretion in response to meals and decreases glucagon levels, leading to improved glycemic control. Additionally, derivatives of this compound have shown potential in inhibiting other enzymes related to metabolic pathways.

NMR spectrum of 209995-38-0

Physical sample testing spectrum (NMR) of 209995-38-0

Safety Information of 209995-38-0

Pictograms

Signal Word

Danger

Hazard Statements

H315 Causes skin irritation
H318 Causes serious eye damage
H319 Causes serious eye irritation
H335 May cause respiratory irritation

Safety Data Sheet

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Bulk Packaging Price Explanation of 209995-38-0

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Purchase Instructions of 209995-38-0

All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

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