Dl-Alpha-Amino-2-Thiopheneacetic Acid

Amino-thiophen-2-YL-acetic acid has several potential applications:

• Pharmaceutical Development: As a candidate for developing anti-inflammatory drugs and cancer therapeutics due to its role as an mPGES-1 inhibitor.
• Chemical Biology: Used in research to probe biochemical pathways involving prostaglandins and other inflammatory mediators.
• Synthetic Chemistry: Acts as a versatile building block for synthesizing other bioactive compounds.

The biological activity of amino-thiophen-2-YL-acetic acid has been explored primarily as an inhibitor of microsomal prostaglandin E synthase-1 (mPGES-1), an enzyme implicated in inflammation and cancer. In vitro studies have shown that derivatives of this compound exhibit selective inhibitory effects against mPGES-1, with promising IC50 values, indicating their potential utility in therapeutic applications targeting inflammatory diseases and cancer.

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All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

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