structure of 2138440-81-8

Pomalidomide-PEG4-COOH

CAS No.: 2138440-81-8 Brand: MolBest
M. Ft.: C24H31N3O10 Cat. No: G1692437
M. Wt.: 521.52 MDL: No record
Storage: 2-8°C
Purity Grade Package Stock Price Quantity
98% RG 100MG In Stock 169 USD
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Applications of 2138440-81-8

Pomalidomide-PEG4-COOH has several applications in research and medicine:

  • Medical Research: It is utilized in studies related to cancer therapy, particularly for targeting specific proteins involved in tumor growth.
  • Drug Release: The compound can be employed in drug delivery systems where controlled release is essential.
  • Nanotechnology: It serves as a building block for creating nanocarriers for therapeutic agents.
  • Cell Culture: Used in various cell culture applications to study protein interactions and cellular responses.

Biological Activity of 2138440-81-8

Pomalidomide-PEG4-COOH exhibits significant biological activity due to its interaction with the cereblon protein, an E3 ubiquitin ligase. This interaction facilitates the degradation of target proteins involved in various cellular processes, including cell signaling and metabolism. The compound's mechanism of action involves forming a ternary complex with cereblon and specific target proteins, leading to their ubiquitination and subsequent proteasomal degradation.

Pharmacokinetics

The pharmacokinetics of Pomalidomide indicate that over 70% of the compound is absorbed following oral administration. Its metabolism primarily involves cytochrome P450-mediated hydroxylation followed by glucuronidation.

NMR spectrum of 2138440-81-8

Physical sample testing spectrum (NMR) of 2138440-81-8

Safety Information of 2138440-81-8

Pictograms

Signal Word

Warning

Hazard Statements

H302 Harmful if swallowed
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation

Safety Data Sheet

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Bulk Packaging Price Explanation of 2138440-81-8

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Purchase Instructions of 2138440-81-8

All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

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