structure of 2216712-66-0

(S)-N-((1,3-Dimethyl-1H-Pyrazol-4-Yl)Sulfonyl)-6-(3-(3,3,3-Trifluoro-2,2-Dimethylpropoxy)-1H-Pyrazol-1-Yl)-2-(2,2,4-Trimethylpyrrolidin-1-Yl)Nicotinamide(CAS 2216712-66-0)

CAS No.: 2216712-66-0 Brand: MolBest
M. Ft.: C26H34F3N7O4S Cat. No: G6708527
M. Wt.: 597.65 MDL: No record
Storage: 2-8°C,Under inert gas. Use: For laboratory research use only
Purity Grade Package Stock Price Quantity
99%
Documents:COANMRSDS
RG 100MG In Stock 303 USD
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Applications of 2216712-66-0

Elexacaftor is primarily indicated for patients with cystic fibrosis who have specific mutations in the CFTR gene, particularly those who are heterozygous for F508del or other mutations that affect protein function. The drug is used in combination with tezacaftor and ivacaftor to maximize therapeutic benefits. Clinical studies have demonstrated significant improvements in lung function (measured by forced expiratory volume) and reductions in respiratory-related hospitalizations among treated patients.

Physical and chemical properties of 2216712-66-0

Acidity coefficient

3.80±0.10(Predicted)

Density

1.38±0.1 g/cm3(Predicted)

Melting Point

206 - 208°C

Molecular Formula

C26H34F3N7O4S

Molecular Weight

597.65

Solubility

<1mg/mL

Storage condition

-20°C Freezer, Under inert atmosphere

Spectrums of 2216712-66-0

Attention:
1.The NMR spectrum displayed on the page is a pre-sale reference spectrum and may differ from that of the actual received batch.
2.The accompanying documentation will include the NMR spectrum and purity analysis data for the shipped batch.
Physical sample testing spectrum (NMR) of 2216712-66-0

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Download SDS of 2216712-66-0

Pictograms

Signal Word

Warning

Hazard Statements

H302 Harmful if swallowed
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation

Safety Data Sheet

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