2-Chloro-5-Nitro-N-Phenylbenzamide

This compound is utilized in various fields:

• Pharmacological Research: It serves as a model compound to study PPARγ pathways and their implications in diseases like diabetes and obesity.
• Drug Development: Its unique properties make it a candidate for developing new therapeutic agents targeting metabolic disorders.
• Chemical Biology: Used in studies investigating lipid metabolism and inflammatory responses in cellular models.

2-Chloro-5-nitro-N-phenylbenzamide acts primarily as an irreversible antagonist of PPARγ. It has been shown to influence lipid metabolism, glucose homeostasis, and inflammatory responses. Interestingly, it exhibits unexpected activation of PPARδ-mediated signaling pathways in macrophages, leading to increased lipogenesis and triglyceride accumulation. This dual action complicates its use in research but also highlights its potential for therapeutic applications in metabolic diseases.

Please email your required order quantity and detailed technical specifications to sales@.
Our sales team will promptly prepare an accurate quotation for your bulk order and provide a comprehensive pricing proposal.

All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.