5-Chlorothiophene-2-Carboxylic Acid

5-Chlorothiophene-2-carboxylic acid finds several applications, particularly in:

• Pharmaceutical Synthesis: It serves as an intermediate in synthesizing various drugs, including rivaroxaban, which is used for treating thromboembolic disorders.
• Agricultural Chemicals: This compound may also be utilized in developing agrochemicals due to its reactivity and ability to form derivatives with biological activity.

Research indicates that 5-chlorothiophene-2-carboxylic acid exhibits significant biological activity. It has been studied for its anticoagulant properties, showing low factor Xa and modest anti-thrombin inhibitory activities with IC${}_{50}$ This suggests potential applications in developing anticoagulant medications.

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