structure of 284461-73-0

Sorafenib(CAS 284461-73-0)

CAS No.: 284461-73-0 Brand: MolBest
M. Ft.: C21H16ClF3N4O3 Cat. No: G5117235
M. Wt.: 464.83 MDL: MFCD06411450
Storage: 2-8°C Use: For laboratory research use only
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99%
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RG 1G In Stock 4 USD
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RG 5G In Stock 8 USD
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RG 25G In Stock 25 USD
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RG 100G In Stock 87 USD
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RG 500G In Stock 815 USD
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Applications of 284461-73-0

Sorafenib is primarily indicated for:

  • Renal Cell Carcinoma: It is used as a first-line treatment for advanced renal cell carcinoma.
  • Hepatocellular Carcinoma: It is also approved for patients with advanced hepatocellular carcinoma who have not undergone surgical resection or liver transplantation.
  • Thyroid Carcinoma: Sorafenib has shown efficacy in treating differentiated thyroid carcinoma that is refractory to radioactive iodine treatment .

Physical and chemical properties of 284461-73-0

Acidity coefficient

12.89±0.70(Predicted)

Boiling Point

523.3±50.0 °C at 760 mmHg

Decomposition

Dangerous products of decomposition: thermal ecomposition may produce toxic gases such as carbon monoxide, carbon dioxide, and nitrogen oxides. /Sorafenib tosylate/

Density

1.5±0.1 g/cm3

Exact Mass

464.086304

Flash Point

270.3±30.1 °C

Index of Refraction

1.626

LogP

3.8

Melting Point

205.6 °C

Molecular Formula

C21H16ClF3N4O3

Molecular Weight

464.825

PSA

92.35000

Stability

Stable if stored as directed; avoid strong oxidizing agents. /Sorafenib tosylate/

Storage condition

-20°C Freezer

Vapour density

4.11X10-14 mm Hg at 25 °C (est)

Vapour Pressure

0.0±1.4 mmHg at 25°C

Water Solubility

100μg/L at 20℃

Spectrums of 284461-73-0

Attention:
1.The NMR spectrum displayed on the page is a pre-sale reference spectrum and may differ from that of the actual received batch.
2.The accompanying documentation will include the NMR spectrum and purity analysis data for the shipped batch.
Physical sample testing spectrum (NMR) of 284461-73-0

Retrosynthesis analysis of 284461-73-0


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Download SDS of 284461-73-0

Pictograms

Signal Word

Danger

Hazard Statements

H351 Suspected of causing cancer
H360 May damage fertility or the unborn child
H360FD May damage fertility; May damage the unborn child
H361 Suspected of damaging fertility or the unborn child
H362 May cause harm to breast-fed children
H372 Causes damage to organs through prolonged or repeated exposure
H400 Very toxic to aquatic life
H402 Harmful to aquatic life
H410 Very toxic to aquatic life with long lasting effects

Safety Data Sheet

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