structure of 30652-11-0

3-Hydroxy-1,2-Dimethyl-4(1H)-Pyridone

CAS No.: 30652-11-0 Brand: MolBest
M. Ft.: C7H9NO2 Cat. No: G8053083
M. Wt.: 139.15 MDL: MFCD00134497
Storage: Store in a cool,dry area.
Purity Grade Package Stock Price Quantity
98% RG 5G In Stock 10 USD
98% RG 25G In Stock 30 USD
98% RG 100G In Stock 94 USD
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Applications of 30652-11-0

Deferiprone is primarily used for:

  • Treatment of Iron Overload: It is indicated for patients with thalassemia major who require chelation therapy due to excessive iron accumulation from blood transfusions.
  • Combination Therapy: It can be used alongside other chelators when monotherapy is ineffective or contraindicated.
  • Potential Antiviral Activity: Research into its effects on HIV indicates possible applications beyond iron chelation.

Biological Activity of 30652-11-0

Deferiprone's primary biological activity is its ability to chelate iron effectively. It has been shown to lower serum ferritin levels and improve iron status in patients with thalassemia and other conditions requiring blood transfusions. Additionally, recent studies suggest that deferiprone may have antiviral properties, specifically in reactivating apoptosis in HIV-infected cells.

Pharmacokinetics
  • Absorption: Rapid absorption occurs in the upper gastrointestinal tract.
  • Half-life: Approximately 1.9 hours.
  • Excretion: About 75-90% of the drug is excreted through the kidneys within 24 hours.

NMR spectrum of 30652-11-0

Physical sample testing spectrum (NMR) of 30652-11-0

Safety Information of 30652-11-0

Pictograms

Signal Word

Warning

Hazard Statements

H302 Harmful if swallowed
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation

Safety Data Sheet

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Purchase Instructions of 30652-11-0

All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

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