structure of 3420-72-2

Flavokawain A

CAS No.: 3420-72-2 Brand: MolBest
M. Ft.: C18H18O5 Cat. No: G9336096
M. Wt.: 314.33 MDL: No record
Storage: Store in a cool,dry area.
Purity Grade Package Stock Price Quantity
98% RG 100MG In Stock 13 USD
98% RG 250MG In Stock 21 USD
98% RG 1G In Stock 40 USD
98% RG 5G In Stock 129 USD
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NMR spectrum of 3420-72-2

Please note that the batch depicted in the provided NMR spectrum may differ from the actual shipped batch; the NMR spectrum corresponding to the shipped batch will be included with the goods.
Physical sample testing spectrum (NMR) of 3420-72-2

Safety Information of 3420-72-2

Pictograms

Signal Word

 Warning

Hazard Statements

 H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation

Safety Data Sheet

Download COA of 3420-72-2

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Applications of 3420-72-2

Flavokawain A has several applications, particularly in:

  • Pharmaceutical Development: Its anticancer and anti-inflammatory properties make it a candidate for drug development targeting various cancers and inflammatory diseases.
  • Nutraceuticals: As a natural product with health benefits, it is being explored for inclusion in dietary supplements aimed at promoting health and wellness.
  • Research: Used as a tool compound in studies investigating cancer biology and inflammatory pathways.

Biological Activity of 3420-72-2

Flavokawain A exhibits significant biological activities, including:

  • Anticancer Properties: It has been shown to induce apoptosis in various cancer cell lines, including bladder cancer cells. The mechanism involves the activation of pro-apoptotic proteins and caspases, leading to mitochondrial dysfunction and cell death.
  • Anti-inflammatory Effects: Flavokawain A suppresses key inflammatory mediators such as inducible nitric oxide synthase and cyclooxygenase-2 by inhibiting the nuclear factor kappa B signaling pathway. This makes it a potential therapeutic agent for inflammatory diseases.
  • Cell Cycle Regulation: It induces cell cycle arrest at different phases depending on the type of cancer cell. For instance, it causes G1 arrest in p53-wild-type bladder cancer cells and G2/M arrest in p53-mutant cells.

Bulk Packaging Price Explanation of 3420-72-2

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Purchase Instructions of 3420-72-2

All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

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