structure of 349-57-5

3-Nitro-5-(Trifluoromethyl)Phenol(CAS 349-57-5)

CAS No.: 349-57-5 Brand: MolBest
M. Ft.: C7H4F3NO3 Cat. No: G9650151
M. Wt.: 207.11 MDL: MFCD04973779
Storage: Store in a cool,dry area. Use: For laboratory research use only
HS CODE: 2908999090
Purity Grade Package Stock Price Quantity
99%
Documents:COANMRGCMSSDS
RG 1G In Stock 8 USD
99%
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RG 5G In Stock 18 USD
99%
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RG 25G In Stock 79 USD
99%
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RG 100G In Stock 477 USD
99%
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RG 500G In Stock 2309 USD
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Applications of 349-57-5

Industry Application Process
Pesticide Manufacturing Key intermediate for synthesizing novel trifluoromethyl aniline-based herbicides and insecticides, e.g., analogues of flumetralin Multi-step synthesis involving nitration, reduction, diazotization, and substitution to convert 3-nitro-5-(trifluoromethyl)phenol into the corresponding aniline derivative, followed by acylation or sulfonylation to construct the active molecular scaffold
Pharmaceutical R&D Synthetic building block for potential antimicrobial and anti-inflammatory drug candidates containing trifluoromethyl aryloxy motifs Pd-catalyzed C–O bond activation or C–H bond functionalization to introduce heterocyclic or alkyl side chains and assemble the target pharmacophore
Materials Science Structural modifier for high-performance liquid crystal monomers and organic optoelectronic materials (e.g., OLED hole-transport layers) Etherification, esterification, or coupling reactions (e.g., Suzuki, Ullmann) to convert the hydroxyl or nitro group into fluorinated rigid conjugated fragments, thereby tuning molecular polarity and thermal stability

Physical and chemical properties of 349-57-5

Acidity coefficient

7.34±0.10(Predicted)

Boiling Point

258.9ºC at 760mmHg

Density

1.554g/cm3

Exact Mass

207.01400

Flash Point

110.4ºC

Index of Refraction

1.507

LogP

2.84240

Melting Point

89-92°C

Molecular Formula

C7H4F3NO3

Molecular Weight

207.10700

PSA

66.05000

Solubility

DMSO (Slightly), Methanol (Slightly)

Storage condition

under inert gas (nitrogen or Argon) at 2-8°C

Spectrums of 349-57-5

Attention:
1.The NMR spectrum displayed on the page is a pre-sale reference spectrum and may differ from that of the actual received batch.
2.The accompanying documentation will include the NMR spectrum and purity analysis data for the shipped batch.
Physical sample testing spectrum (NMR) of 349-57-5

Retrosynthesis analysis of 349-57-5


Q&A for CAS 349-57-5

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Download SDS of 349-57-5

Pictograms

Signal Word

Warning

Hazard Statements

H302+H312+H332 Harmful if swallowed, in contact with skin or if inhaled
H302 Harmful if swallowed
H312 Harmful in contact with skin
H315 Causes skin irritation
H319 Causes serious eye irritation
H332 Harmful if inhaled
H335 May cause respiratory irritation

Safety Data Sheet

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