(R)-2,5-Ddioxopyrrolidin-1-Yl 2-((Tert-Butoxycarbonyl)Amino)-3-Phenylpropanoate(CAS 3674-18-8)
| Purity | Grade | Package | Stock | Price | Quantity |
| 99% | RG | 5G | In Stock | 7 USD
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| 99% | RG | 25G | In Stock | 22 USD
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| 99% | RG | 100G | In Stock | 85 USD
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| 99% | RG | 500G | In Stock | 422 USD
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Applications of 3674-18-8
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Protected D-phenylalanine intermediate for chiral drug synthesis | Used for Nα-tert-butoxycarbonyl (BOC) protection and active esterification of D-phenylalanine residues in solid-phase peptide synthesis (SPPS), facilitating subsequent coupling to resin or amino acids |
| Peptide Chemistry | Construction of bioactive peptides containing D-phenylalanine | Undergoes amidation with amine components under basic conditions (e.g., DIPEA/DCM); the OSu (N-hydroxysuccinimide) group provides high reactivity and favorable leaving-group properties |
| Organic Synthesis | Chiral building block for asymmetric catalysis and structural modification | Serves as an optically pure D-configured substrate in fine synthetic steps such as enzymatic resolution, chiral ligand derivatization, or cyclization reactions |
Physical and chemical properties of 3674-18-8
Acidity coefficient |
10.76±0.46(Predicted) |
|---|---|
Density |
1.28±0.1 g/cm3 |
Exact Mass |
362.147797 |
H Bond Acceptors |
4 |
H Bond Donors |
1 |
Index of Refraction |
1.562 |
LogP |
1.51 |
Melting Point |
152-153 ºC |
Molecular Formula |
C18H22N2O6 |
Molecular Weight |
362.377 |
PSA |
102.01000 |
Storage condition |
−20°C |
Water Solubility |
Very slightly soluble (0.33 g/L) (25 ºC) |
Spectrums of 3674-18-8
1.The NMR spectrum displayed on the page is a pre-sale reference spectrum and may differ from that of the actual received batch.
2.The accompanying documentation will include the NMR spectrum and purity analysis data for the shipped batch.
Cas:13734-34-4
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Q&A for CAS 3674-18-8
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Download SDS of 3674-18-8
Pictograms |
 |
|---|---|
Signal Word |
Warning |
Hazard Statements |
H302 Harmful if swallowed H315 Causes skin irritation H319 Causes serious eye irritation H335 May cause respiratory irritation |
Safety Data Sheet |
Download COA of 3674-18-8
Operate under the ISO 9001 system
