structure of 3680-69-1

6-Chloro-7-deazapurine

CAS No.: 3680-69-1 Brand: MolBest
M. Ft.: C6H4ClN3 Cat. No: G5186543
M. Wt.: 153.57 MDL: MFCD01686865
Storage: Store in a cool,dry area.
Purity Grade Package Stock Price Quantity
98% RG 1G In Stock 2 USD
98% RG 5G In Stock 4 USD
98% RG 25G In Stock 14 USD
98% RG 100G In Stock 52 USD
98% RG 500G In Stock 250 USD
98% RG 2.5KG In Stock 1557 USD
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Applications of 3680-69-1

4-Chloro-7H-pyrrolo[2,3-d]pyrimidine is primarily utilized as an intermediate in pharmaceutical synthesis:

  • Drug Development: It is essential in preparing active pharmaceutical ingredients such as ruxolitinib, tofacitinib, and baricitinib, which are used for treating various conditions including cancer and autoimmune diseases.
  • Research

Biological Activity of 3680-69-1

The biological activity of 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine is significant, particularly in the context of drug development:

  • Kinase Inhibition: It serves as a scaffold for developing potent kinase inhibitors that modulate cellular signaling pathways associated with cancer progression and inflammatory disorders.
  • Anticancer Potential: Derivatives of this compound have shown promise as anticancer agents, with molecular docking studies indicating favorable binding affinities against targets like the Bcl2 anti-apoptotic protein.
  • Inflammatory Disease Treatment: The compound is also explored for potential applications in treating inflammatory diseases due to its ability to down-regulate genes involved in inflammation.

NMR spectrum of 3680-69-1

Physical sample testing spectrum (NMR) of 3680-69-1

Safety Information of 3680-69-1

Pictograms

Signal Word

Danger

Hazard Statements

H301 Toxic if swallowed
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation

Safety Data Sheet

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Bulk Packaging Price Explanation of 3680-69-1

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Purchase Instructions of 3680-69-1

All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

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