structure of 38186-82-2

2-Chloro-3-methyl-5-aminopyridine

CAS No.: 38186-82-2 Brand: MolBest
M. Ft.: C6H7ClN2 Cat. No: G2614011
M. Wt.: 142.59 MDL: MFCD03095087
Storage: Store in a cool,dry area.
Purity Grade Package Stock Price Quantity
98% RG 25G In Stock 20 USD
98% RG 100G In Stock 75 USD
98% RG 500G In Stock 360 USD
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Applications of 38186-82-2

6-Chloro-5-methylpyridin-3-amine has diverse applications across various fields:

  • Chemistry: Serves as a building block for synthesizing more complex organic compounds.
  • Biology: Used in studies related to drug development and biological systems.
  • Medicine: Acts as a precursor for drugs targeting various diseases.
  • Industry: Employed in producing agrochemicals, dyes, and other industrial chemicals.

Biological Activity of 38186-82-2

The biological activity of 6-Chloro-5-methylpyridin-3-amine is primarily linked to its role as an intermediate in the synthesis of pharmaceuticals. Notably, it is involved in the production of lumacaftor, a drug used in the treatment of cystic fibrosis. The compound exhibits high gastrointestinal absorption and is permeable to the blood-brain barrier, suggesting potential neurological applications.

Mechanism of Action

While specific cellular effects remain largely unexplored due to limited research, its involvement in synthesizing drugs targeting defective proteins indicates significant biological relevance. Lumacaftor improves CFTR protein function, which is critical for cystic fibrosis patients.

NMR spectrum of 38186-82-2

Physical sample testing spectrum (NMR) of 38186-82-2

Safety Information of 38186-82-2

Pictograms

Signal Word

Danger

Hazard Statements

H302 Harmful if swallowed
H315 Causes skin irritation
H318 Causes serious eye damage
H335 May cause respiratory irritation

Safety Data Sheet

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Purchase Instructions of 38186-82-2

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