structure of 4008-48-4

Nitroxoline

CAS No.: 4008-48-4 Brand: MolBest
M. Ft.: C9H6N2O3 Cat. No: G2995211
M. Wt.: 190.16 MDL: MFCD00006791
Storage: Store in a cool,dry area.
Purity Grade Package Stock Price Quantity
98% RG 5G In Stock 4 USD
98% RG 25G In Stock 12 USD
98% RG 100G In Stock 47 USD
98% RG 500G In Stock 222 USD
98% RG 2.5KG In Stock 448 USD
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Applications of 4008-48-4

Nitroxoline has several notable applications:

  • Medical Use: Primarily used as an antibacterial agent for treating urinary tract infections.
  • Anticancer Research: Investigated for its potential use in cancer therapy due to its ability to induce oxidative stress and inhibit tumor cell proliferation.
  • Biofilm Treatment: Used in studies aimed at disrupting bacterial biofilms, particularly in chronic infections where biofilms pose a significant barrier to treatment.

Biological Activity of 4008-48-4

Nitroxoline exhibits a broad spectrum of biological activities:

  • Antibacterial Activity: It is effective against a variety of pathogens commonly associated with urinary tract infections.
  • Anticancer Properties: Recent studies have shown that nitroxoline can inhibit cancer cell proliferation by inducing oxidative stress and inhibiting cathepsin B, an enzyme involved in tumor progression. This suggests potential for repurposing nitroxoline as an anticancer agent.
  • Biofilm Disruption: Nitroxoline's ability to chelate metal ions makes it effective at reducing biofilm density in bacterial infections, thus allowing for better penetration of immune cells.

NMR spectrum of 4008-48-4

Physical sample testing spectrum (NMR) of 4008-48-4

Safety Information of 4008-48-4

Pictograms

Signal Word

Danger

Hazard Statements

H301 Toxic if swallowed
H302 Harmful if swallowed
H311 Toxic in contact with skin
H315 Causes skin irritation
H319 Causes serious eye irritation
H331 Toxic if inhaled
H335 May cause respiratory irritation

Safety Data Sheet

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Bulk Packaging Price Explanation of 4008-48-4

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Purchase Instructions of 4008-48-4

All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

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