structure of 4043-88-3

(S)-2,5-Dihydro-1H-Pyrrole-2-Carboxylic Acid

CAS No.: 4043-88-3 Brand: MolBest
M. Ft.: C5H7NO2 Cat. No: G5998104
M. Wt.: 113.11 MDL: MFCD00065964
Storage: Store in a cool,dry area.
Purity Grade Package Stock Price Quantity
97% RG 100MG In Stock 17 USD
97% RG 250MG In Stock 31 USD
97% RG 5G In Stock 587 USD
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Applications of 4043-88-3

3,4-Dehydro-L-proline has several applications across different fields:

  • Research Tool: It is widely used in plant biology research to study the function of HRGPs and their role in cell wall integrity and development.
  • Pharmaceuticals: Due to its inhibitory properties on prolyl-4-hydroxylases, it may have potential applications in drug development for conditions related to collagen synthesis and fibrosis.
  • Synthetic Chemistry: Its unique structure allows it to be used as a building block in organic synthesis for creating more complex molecules.

Biological Activity of 4043-88-3

The biological activity of 3,4-dehydro-L-proline is primarily linked to its role as an inhibitor of prolyl-4-hydroxylase. By inhibiting this enzyme, 3,4-dehydro-L-proline affects the stability and functionality of hydroxyproline-rich glycoproteins (HRGPs), which are essential for plant growth and development. Experimental studies have shown that treatment with this compound leads to increased expression of metacaspases involved in programmed cell death pathways within roots.

Moreover, 3,4-dehydro-L-proline has been observed to induce morphological changes in root cells, resulting in ruptured epidermal cells and altered cell structures under microscopic examination. Its selective inhibition properties make it a valuable tool for studying the roles of specific proteins in cellular processes.

NMR spectrum of 4043-88-3

Physical sample testing spectrum (NMR) of 4043-88-3

Safety Information of 4043-88-3

Pictograms

Signal Word

Warning

Hazard Statements

H302 Harmful if swallowed
H315 Causes skin irritation
H319 Causes serious eye irritation
H332 Harmful if inhaled
H335 May cause respiratory irritation

Safety Data Sheet

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Purchase Instructions of 4043-88-3

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