structure of 4342-03-4

Dacarbazine(CAS 4342-03-4)

CAS No.: 4342-03-4 Brand: MolBest
M. Ft.: C6H10N6O Cat. No: G9233499
M. Wt.: 182.18 MDL: MFCD00057167
Storage: 2-8°C Use: For laboratory research use only
HS CODE: 2934999090
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RG 5G In Stock 47 USD
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Applications of 4342-03-4

Dacarbazine is primarily used in oncology for:

  • Metastatic Malignant Melanoma: Often administered as a single agent or in combination with other chemotherapeutic agents.
  • Hodgkin Lymphoma: Commonly part of combination regimens like ABVD (Adriamycin, Bleomycin, Vinblastine, Dacarbazine).
  • Soft Tissue Sarcoma: Utilized in specific treatment protocols.

It is also included on the World Health Organization's List of Essential Medicines due to its critical role in cancer treatment.

Physical and chemical properties of 4342-03-4

Acidity coefficient

pKa 4.42 (Uncertain)

Boiling Point

456.3±55.0 °C at 760 mmHg

carcinogen classification

2B (Vol. 26, Sup 7) 1987

Decomposition

When heated to decomposition /temperature unspecified/, it emits toxic fumes of NOx.

Density

1.5±0.1 g/cm3

Exact Mass

182.091614

Flash Point

229.7±31.5 °C

Index of Refraction

1.678

LogP

log P = -0.24

Melting Point

Melting point: 250-255 °C (explosive decomposition)

Merck

14,2798

Molecular Formula

C6H10N6O

Molecular Weight

182.183

PSA

99.73000

Stability

Dacarbazine is extremely light sensitive and rapidly undergoes photodecomposition. Dacarbazine is sensitive to oxidation but is stable in neutral solutions in the absence of light.

Storage condition

2-8°C

Vapour Pressure

0.0±1.1 mmHg at 25°C

Spectrums of 4342-03-4

Attention:
1.The NMR spectrum displayed on the page is a pre-sale reference spectrum and may differ from that of the actual received batch.
2.The accompanying documentation will include the NMR spectrum and purity analysis data for the shipped batch.
Physical sample testing spectrum (NMR) of 4342-03-4

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Download SDS of 4342-03-4

Pictograms

Signal Word

Danger

Hazard Statements

H302+H312+H332 Harmful if swallowed, in contact with skin or if inhaled
H302 Harmful if swallowed
H312 Harmful in contact with skin
H315 Causes skin irritation
H319 Causes serious eye irritation
H332 Harmful if inhaled
H335 May cause respiratory irritation
H340 May cause genetic defects
H350 May cause cancer

Safety Data Sheet

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