N-(2-Chloropyrimidin-4-Yl)-N,2,3-Trimethyl-2H-Indazol-6-Amine(CAS 444731-75-3)
| Purity | Grade | Package | Stock | Price | Quantity |
| 98% | RG | 250MG | In Stock | 2 USD
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| 98% | RG | 1G | In Stock | 3 USD
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| 98% | RG | 5G | In Stock | 15 USD
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| 98% | RG | 25G | In Stock | 75 USD
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| 98% | RG | 100G | In Stock | 538 USD
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| 98% | RG | 500G | In Stock | 2584 USD
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| Bulk Packaging | 25KG | substantially lower unit cost than small-pack SKUs. Contact us for a fast quotation. | |||
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Your region is eligible for ordering. Available NMR Spectrum
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Applications of 444731-75-3
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Erlotinib derivatives and antitumor drug intermediates | Serves as a key structural unit; the chlorine atom on the pyrimidine ring undergoes nucleophilic substitution with aromatic amines to construct the kinase inhibitor scaffold featuring an indazole structure |
| Pharmaceutical Chemicals | Targeted anticancer drug development | Used in synthesizing fourth-generation inhibitor candidates targeting EGFR (epidermal growth factor receptor) or HER2 |
Physical and chemical properties of 444731-75-3
Acidity coefficient |
2.82±0.30(Predicted) |
|---|---|
Boiling Point |
524.4±35.0 °C at 760 mmHg |
Density |
1.3±0.1 g/cm3 |
Exact Mass |
287.093781 |
Flash Point |
271.0±25.9 °C |
Index of Refraction |
1.673 |
LogP |
2.90 |
Melting Point |
167-173℃ |
Molecular Formula |
C14H14ClN5 |
Molecular Weight |
287.747 |
PSA |
46.84000 |
Solubility |
Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Very Slightly) |
Stability |
Hygroscopic |
Storage condition |
under inert gas (nitrogen or Argon) at 2-8°C |
Vapour Pressure |
0.0±1.4 mmHg at 25°C |
Spectrums of 444731-75-3
1.The NMR spectrum displayed on the page is a pre-sale reference spectrum and may differ from that of the actual received batch.
2.The accompanying documentation will include the NMR spectrum and purity analysis data for the shipped batch.
Retrosynthesis analysis of 444731-75-3
Cas:444731-74-2
Cas:74-88-4
Cas:616-38-6
Q&A for CAS 444731-75-3
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Yes. Batch COA available matches the actual shipment. COAs shown online are for reference or from previous batches.
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Download SDS of 444731-75-3
Pictograms |
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|---|---|
Signal Word |
Danger |
Hazard Statements |
H301 Toxic if swallowed H302 Harmful if swallowed H319 Causes serious eye irritation H341 Suspected of causing genetic defects H361 Suspected of damaging fertility or the unborn child H362 May cause harm to breast-fed children H412 Harmful to aquatic life with long lasting effects |
Safety Data Sheet |
Download COA of 444731-75-3
Operate under the ISO 9001 system
