((3Ar,5R,5As,8As,8Br)-2,2,7,7-Tetramethyltetrahydro-3Ah-Bis([1,3]Dioxolo)[4,5-B:4’,5’-D]Pyran-5-Yl)Methyl 4-Methylbenzenesulfonate(CAS 4478-43-7)
| Purity | Grade | Package | Stock | Price | Quantity |
| 98% | RG | 250MG | In Stock | 3 USD
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| 98% | RG | 1G | In Stock | 20 USD
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| 98% | RG | 5G | In Stock | 34 USD
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| 98% | RG | 25G | In Stock | 121 USD
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| 98% | RG | 100G | In Stock | 482 USD
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| Bulk Packaging | 5KG | substantially lower unit cost than small-pack SKUs. Contact us for a fast quotation. | |||
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Applications of 4478-43-7
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a glycosylation intermediate for synthesizing complex oligosaccharides, glycosidic drugs, and antitumor antibiotics (e.g., doxorubicin derivatives) | Selectively protects the 6-hydroxyl group of D-galactose derivatives using p-toluenesulfonyl chloride as the sulfonylation reagent under anhydrous conditions, followed by acid-catalyzed ketalization with acetone to form an isopropylidene acetal—enabling construction of stereoselective glycosyl ring structures |
| Biochemistry | Used to synthesize model compounds of glycoproteins and glycolipids, and as substrates in glycosidase studies | Functions as a chiral building block, coupled to peptide chains or lipid scaffolds via enzymatic or chemical conjugation reactions to investigate carbohydrate recognition mechanisms and molecular interactions |
| Organic Synthesis | Used as a highly selective glycosyl donor for constructing β-galactosidic linkages | Undergoes Koenigs–Knorr-type glycosylation with alcohols or glycosyl acceptors under Lewis acid catalysis (e.g., BF₃·Et₂O) to achieve stereocontrol of the 1,2-cis configuration |
| Pharmaceutical R&D | Used in developing antiviral and antibacterial glycoside lead compounds | Serves as the core galactose-derived scaffold; subsequent deprotection and functional group modifications yield inhibitors targeting pathogen carbohydrate-binding proteins |
Physical and chemical properties of 4478-43-7
Boiling Point |
513.7ºC at 760 mmHg |
|---|---|
Density |
1.23 g/cm3 |
Exact Mass |
414.13500 |
Flash Point |
264.5ºC |
Index of Refraction |
1.505 |
LogP |
3.17760 |
Melting Point |
92°C(lit.) |
Molecular Formula |
C19H26O8S |
Molecular Weight |
414.47000 |
PSA |
97.90000 |
Spectrums of 4478-43-7
1.The NMR spectrum displayed on the page is a pre-sale reference spectrum and may differ from that of the actual received batch.
2.The accompanying documentation will include the NMR spectrum and purity analysis data for the shipped batch.
Retrosynthesis analysis of 4478-43-7
Cas:4064-06-6
Cas:6748-86-3
Cas:98-59-9
Q&A for CAS 4478-43-7
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Download COA of 4478-43-7
Operate under the ISO 9001 system
