structure of 451-13-8

2-(2,5-Dihydroxyphenyl)Acetic Acid

CAS No.: 451-13-8 Brand: MolBest
M. Ft.: C8H8O4 Cat. No: G2780767
M. Wt.: 168.15 MDL: MFCD00004324
Storage: 2-8°C
Purity Grade Package Stock Price Quantity
97% RG 100MG In Stock 51 USD
97% RG 250MG In Stock 87 USD
97% RG 1G In Stock 236 USD
97% RG 5G In Stock 1131 USD
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NMR spectrum of 451-13-8

Please note that the batch depicted in the provided NMR spectrum may differ from the actual shipped batch; the NMR spectrum corresponding to the shipped batch will be included with the goods.
Physical sample testing spectrum (NMR) of 451-13-8

Safety Information of 451-13-8

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Signal Word

Warning

Hazard Statements

H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation

Safety Data Sheet

Download COA of 451-13-8

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Applications of 451-13-8

Homogentisic acid has several applications:

  • Clinical Diagnostics: It serves as a biomarker for alkaptonuria, where its presence in urine indicates metabolic dysfunction.
  • Research: Used in studies investigating oxidative stress and metabolic disorders related to amino acid catabolism.
  • Pharmaceuticals: Investigated for potential therapeutic interventions targeting oxidative stress pathways associated with its accumulation.

Biological Activity of 451-13-8

Homogentisic acid is biologically significant primarily due to its role in metabolic pathways involving phenylalanine and tyrosine. Its accumulation in tissues leads to oxidative stress and inflammation, contributing to joint pain and other symptoms associated with alkaptonuria. The pigment formed from its oxidation can deposit in cartilage, leading to visible darkening and potentially severe joint issues over time.

Bulk Packaging Price Explanation of 451-13-8

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Purchase Instructions of 451-13-8

All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

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