structure of 455-71-0

Methyl 6-Fluoropicolinate

CAS No.: 455-71-0 Brand: MolBest
M. Ft.: C7H6FNO2 Cat. No: G2879516
M. Wt.: 155.13 MDL: MFCD11110421
Storage: Store in a cool,dry area.
Purity Grade Package Stock Price Quantity
98% RG 100MG In Stock 7 USD
98% RG 250MG In Stock 9 USD
98% RG 1G In Stock 15 USD
98% RG 5G In Stock 47 USD
98% RG 25G In Stock 223 USD
98% RG 100G In Stock 1282 USD
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Applications of 455-71-0

Methyl 6-fluoropicolinate is utilized across various fields:

  • Pharmaceuticals: As an intermediate in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting cancer treatment and other serious diseases.
  • Agrochemicals: Its derivatives are explored as herbicides and pesticides due to their biological activity against specific plant pathogens.
  • Materials Science: Employed in developing new materials and ligands for catalysis, particularly in organic synthesis.

Biological Activity of 455-71-0

Methyl 6-fluoropicolinate exhibits notable biological activities:

  • Anticancer Properties: It has been identified as a precursor for synthesizing selective antagonists of BCL-X_L, which are relevant in treating chronic lymphocytic leukemia. These compounds have shown significant potency (14 nM) against cancer cells.
  • Metal Chelation: The hydrolyzed form acts as a chelator, which may enhance the bioavailability of certain metal-based drugs and improve their therapeutic efficacy.

NMR spectrum of 455-71-0

Physical sample testing spectrum (NMR) of 455-71-0

Safety Information of 455-71-0

Pictograms

Signal Word

Warning

Hazard Statements

H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation

Safety Data Sheet

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Bulk Packaging Price Explanation of 455-71-0

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Purchase Instructions of 455-71-0

All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

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