structure of 4857-04-9

2-Chloromethylbenzimidazole

CAS No.: 4857-04-9 Brand: MolBest
M. Ft.: C8H7ClN2 Cat. No: G2012139
M. Wt.: 166.61 MDL: MFCD00005602
Storage: Store in a cool,dry area.
Purity Grade Package Stock Price Quantity
96% RG 1G In Stock 4 USD
96% RG 25G In Stock 18 USD
96% RG 100G In Stock 68 USD
96% RG 500G In Stock 430 USD
96% RG 2.5KG In Stock 2133 USD
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Applications of 4857-04-9

2-(Chloromethyl)benzimidazole serves as an important intermediate in the synthesis of various pharmaceuticals and agrochemicals. Its derivatives are explored for applications such as:

  • Antifungal Agents: Many derivatives exhibit potent antifungal activity, making them candidates for agricultural fungicides .
  • Pharmaceuticals: The compound is used in developing drugs due to its biological activity against various pathogens .
  • Organic Synthesis: It acts as a building block for synthesizing more complex organic molecules.

Biological Activity of 4857-04-9

2-(Chloromethyl)benzimidazole and its derivatives have been studied for their biological activities, particularly their antifungal properties. Research has shown that several derivatives synthesized from this compound exhibit significant antifungal activity against various phytopathogenic fungi. For instance, specific derivatives have demonstrated strong inhibition rates against fungi such as Colletotrichum gloeosporioides and Fusarium solani, with IC$_{50}$ values comparable to commercial fungicides . Additionally, some studies suggest that modifications on the benzimidazole structure can enhance biological activity through structure-activity relationship analysis .

NMR spectrum of 4857-04-9

Physical sample testing spectrum (NMR) of 4857-04-9

Safety Information of 4857-04-9

Pictograms

Signal Word

Warning

Hazard Statements

H302 Harmful if swallowed
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation

Safety Data Sheet

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Purchase Instructions of 4857-04-9

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