structure of 486-74-8

Quinoline-4-Carboxylic Acid

CAS No.: 486-74-8 Brand: MolBest
M. Ft.: C10H7NO2 Cat. No: G8713984
M. Wt.: 173.17 MDL: MFCD00006782
Storage: Store in a cool,dry area.
Purity Grade Package Stock Price Quantity
98% RG 1G In Stock 7 USD
98% RG 5G In Stock 20 USD
98% RG 25G In Stock 90 USD
98% RG 100G In Stock 542 USD
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Applications of 486-74-8

Quinoline-4-carboxylic acid has several applications:

  • Pharmaceuticals: It serves as a scaffold for designing new drugs with antitumor and antimicrobial properties.
  • Agricultural Chemicals: Its derivatives are explored for use in developing agrochemicals due to their bioactivity against pests.
  • Dyes and Pigments: Quinoline derivatives are utilized in dye synthesis due to their vibrant colors and stability.

Biological Activity of 486-74-8

Quinoline-4-carboxylic acid and its derivatives exhibit a range of biological activities, including:

  • Antitumor Activity: Various derivatives have shown selective cytotoxic effects against cancer cell lines, such as H460 and MKN-45, indicating potential as anticancer agents.
  • Antileishmanial Activity: Some derivatives have been evaluated for their effectiveness against Leishmania donovani, showing promising results in inhibiting the growth of this parasite.
  • Inhibition of Sirtuins: Recent studies have identified quinoline-4-carboxylic acid derivatives as selective inhibitors of SIRT3, an enzyme implicated in cancer metabolism.

NMR spectrum of 486-74-8

Physical sample testing spectrum (NMR) of 486-74-8

Safety Information of 486-74-8

Pictograms

Signal Word

Warning

Hazard Statements

H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation

Safety Data Sheet

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Purchase Instructions of 486-74-8

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