5-Fluorouracil
| Purity | Grade | Package | Stock | Price | Quantity |
|---|---|---|---|---|---|
| 99% | RG | 500G | In Stock | 68 USD | |
Your region is eligible for ordering. Should you have any questions, please contact us by Email. |
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Promotion
Applications of 51-21-8
5-Fluorouracil is predominantly used in oncology for treating:
- Colorectal cancer
- Breast cancer
- Basal cell carcinoma
- Other solid tumors
It can be administered intravenously or topically for certain dermatological conditions. Combination therapies with agents such as leucovorin enhance its effectiveness by stabilizing the enzyme-inhibitor complex formed during its action.
Biological Activity of 51-21-8
The primary mechanism of action of 5-Fluorouracil involves the inhibition of thymidylate synthase, an enzyme critical for the synthesis of dTMP from deoxyuridine monophosphate (dUMP). This action leads to a depletion of dTMP, causing thymineless death in cancer cells that rely on rapid DNA replication. Furthermore, 5-Fluorouracil has been shown to increase the expression of p53, a tumor suppressor protein that plays a significant role in regulating the cell cycle and preventing tumor formation.
NMR spectrum of 51-21-8
Safety Information of 51-21-8
Download COA of 51-21-8
Bulk Packaging Price Explanation of 51-21-8
Please email your required order quantity and detailed technical specifications to sales@.
Our sales team will promptly prepare an accurate quotation for your bulk order and provide a comprehensive pricing proposal.
Purchase Instructions of 51-21-8
All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.
These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.
Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.
New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.
