structure of 51-24-1

3,3′,5-TrIIodothyroacetic Acid

CAS No.: 51-24-1 Brand: MolBest
M. Ft.: C14H9I3O4 Cat. No: G9684954
M. Wt.: 621.93 MDL: No record
Storage: 2-8°C
Purity Grade Package Stock Price Quantity
90% RG 100MG In Stock 16 USD
90% RG 250MG In Stock 31 USD
90% RG 1G In Stock 76 USD
90% RG 5G In Stock 272 USD
90% RG 25G In Stock 1303 USD
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NMR spectrum of 51-24-1

Please note that the batch depicted in the provided NMR spectrum may differ from the actual shipped batch; the NMR spectrum corresponding to the shipped batch will be included with the goods.
Physical sample testing spectrum (NMR) of 51-24-1

Safety Information of 51-24-1

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Signal Word

Warning

Hazard Statements

H302 Harmful if swallowed
H312 Harmful in contact with skin
H332 Harmful if inhaled

Safety Data Sheet

Download COA of 51-24-1

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Applications of 51-24-1

Tiratricol has several applications in clinical settings:

  • Thyroid Hormone Resistance Syndrome: It is used as a treatment option for patients who do not respond adequately to conventional thyroid hormone therapies.
  • Thyroid Cancer: In combination with levothyroxine, tiratricol helps suppress thyroid-stimulating hormone production.
  • Hyperlipidemia: Investigated for its potential benefits in managing lipid profiles.
  • Weight Management: Marketed historically as a weight loss aid, though this use has faced regulatory scrutiny due to safety concerns.

Biological Activity of 51-24-1

Tiratricol demonstrates distinct biological activities that mimic those of natural thyroid hormones. It has been shown to suppress pituitary thyroid-stimulating hormone secretion effectively, requiring lower doses of levothyroxine to achieve equivalent suppression compared to placebo treatments. Clinical studies indicate that tiratricol can enhance hepatic effects, leading to increased concentrations of sex hormone binding globulin and ferritin while reducing serum cholesterol and low-density lipoprotein cholesterol levels. Its action on skeletal metabolism includes elevated osteocalcin levels without significant changes in serum calcium or parathyroid hormone levels, indicating a selective effect on bone metabolism.

Bulk Packaging Price Explanation of 51-24-1

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Purchase Instructions of 51-24-1

All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

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