structure of 5144-89-8

1,10-Phenanthroline Monohydrate

CAS No.: 5144-89-8 Brand: MolBest
M. Ft.: C12H10N2O Cat. No: G2814842
M. Wt.: 198.22 MDL: MFCD00149973
Storage: Store in a cool,dry area.
Purity Grade Package Stock Price Quantity
99% RG 5G In Stock 2 USD
99% RG 100G In Stock 12 USD
99% RG 500G In Stock 50 USD
99% RG 2.5KG In Stock 245 USD
99% RG 10KG In Stock 949 USD
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Applications of 5144-89-8

1,10-Phenanthroline monohydrate has diverse applications across several fields:

  • Metal Ion Detection: Its ability to form colored complexes allows for the detection of various metal ions through colorimetric or spectrophotometric methods.
  • Drug Development: It serves as a structural scaffold or ligand in drug molecules that exhibit biological activity against cancer and bacterial infections.
  • Materials Science: Utilized in the formation of metal-organic frameworks (MOFs) and photosensitive materials due to its coordination properties.
  • Photochemistry: Acts as a photosensitizer in photo

Biological Activity of 5144-89-8

1,10-Phenanthroline has demonstrated significant biological activity, particularly as an inhibitor of metallopeptidases. It primarily targets zinc-dependent enzymes by chelating the metal ion necessary for their catalytic function, leading to enzyme inactivity. This property makes it a valuable tool in biochemical research for studying enzyme mechanisms and potential therapeutic applications . Furthermore, derivatives of 1,10-phenanthroline have shown anti-cancer and antibacterial properties, indicating its potential in drug development .

NMR spectrum of 5144-89-8

Physical sample testing spectrum (NMR) of 5144-89-8

Safety Information of 5144-89-8

Pictograms

Signal Word

Danger

Hazard Statements

H301 Toxic if swallowed
H400 Very toxic to aquatic life
H410 Very toxic to aquatic life with long lasting effects

Safety Data Sheet

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