structure of 516-54-1

Allopregnanolone(CAS 516-54-1)

CAS No.: 516-54-1 Brand: MolBest
M. Ft.: C21H34O2 Cat. No: G3177212
M. Wt.: 318.5 MDL: No record
Storage: Store in a cool,dry area. Use: For laboratory research use only
Purity Grade Package Stock Price Quantity
98%
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RG 100MG In Stock 17 USD
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RG 250MG In Stock 36 USD
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RG 1G In Stock 80 USD
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RG 5G In Stock 226 USD
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RG 25G In Stock 1083 USD
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Applications of 516-54-1

Allopregnanolone has several notable applications:

  • Therapeutic Use: It is used clinically as brexanolone for treating postpartum depression, administered via intravenous infusion.
  • Research Tool: Due to its role as a GABA A receptor modulator, it serves as an important tool in neuroscience research to study anxiety disorders and other mood-related conditions.
  • Potential Treatment for Other Disorders: Ongoing studies are investigating its efficacy in treating conditions like premenstrual dysphoric disorder and post-traumatic stress disorder due to its neuroactive properties.

Physical and chemical properties of 516-54-1

Acidity coefficient

15.12±0.70(Predicted)

Appearance of Characters

White solid

Boiling Point

431.2±18.0 °C at 760 mmHg

BRN

3211363

Density

1.1±0.1 g/cm3

Exact Mass

318.255890

Flash Point

183.9±13.8 °C

Index of Refraction

1.524

LogP

4.89

Melting Point

177 °C

Merck

13,272

Molecular Formula

C21H34O2

Molecular Weight

318.493

PSA

37.30000

Solubility

chloroform: 20 mg/mL, clear, colorless

Specific rotation

D +87.7° (abs alc)

Stability

Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.

Storage condition

Store at RT

Vapour Pressure

0.0±2.3 mmHg at 25°C

Water Solubility

chloroform: 20 mg/mL, clear, colorless

Spectrums of 516-54-1

Attention:
1.The NMR spectrum displayed on the page is a pre-sale reference spectrum and may differ from that of the actual received batch.
2.The accompanying documentation will include the NMR spectrum and purity analysis data for the shipped batch.
Physical sample testing spectrum (NMR) of 516-54-1

Retrosynthesis analysis of 516-54-1

  • Route#1

    Cas:63-05-8
    Cas:516-54-1

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