structure of 51805-45-9

Tris(2-Carboxyethyl)Phosphine Hydrochloride

CAS No.: 51805-45-9 Brand: MolBest
M. Ft.: C9H16ClO6P Cat. No: G6493304
M. Wt.: 286.65 MDL: MFCD00145469
Storage: 2-8°C
Purity Grade Package Stock Price Quantity
98% RG 1G In Stock 2 USD
98% RG 5G In Stock 2 USD
98% RG 500G In Stock 224 USD
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Applications of 51805-45-9

Tris(2-carboxyethyl)phosphine hydrochloride finds extensive applications in:

  • Protein Chemistry: Used to reduce disulfide bonds in proteins prior to analysis or modification.
  • Electrophoresis: Facilitates the preparation of samples for gel electrophoresis by maintaining proteins in their reduced state.
  • Labeling Reactions: Useful in labeling cysteine residues with maleimides due to its ability to prevent disulfide bond formation.

Biological Activity of 51805-45-9

In biological systems, tris(2-carboxyethyl)phosphine hydrochloride is recognized for its ability to maintain the reduced state of thiols, which is essential for proper protein folding and function. Unlike other reducing agents such as dithiothreitol, it does not interfere with subsequent reactions involving thiol groups, making it a preferred choice in various biochemical assays. Additionally, its stability across a range of pH levels enhances its utility in biological experiments.

NMR spectrum of 51805-45-9

Physical sample testing spectrum (NMR) of 51805-45-9

Safety Information of 51805-45-9

Pictograms

Signal Word

Danger

Hazard Statements

H314 Causes severe skin burns and eye damage
H318 Causes serious eye damage

Safety Data Sheet

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Purchase Instructions of 51805-45-9

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