N-tert-Butoxycarbonyl-1,6-hexanediamine(CAS 51857-17-1)
UN No.:
UN 2735 8 /PG II
| Purity | Grade | Package | Stock | Price | Quantity |
| 98% | RG | 1G | In Stock | 3 USD
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| 98% | RG | 5G | In Stock | 12 USD
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| 98% | RG | 25G | In Stock | 29 USD
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| 98% | RG | 100G | In Stock | 99 USD
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| 98% | RG | 500G | In Stock | 474 USD
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Applications of 51857-17-1
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Amino acid protecting reagent for temporary protection of the lysine side-chain amino group in peptide synthesis | Prepared via reaction of isocyanate with 6-aminohexylamine in solid-phase peptide synthesis (SPPS), followed by coupling to the carboxyl group of the target amino acid or peptide chain; the tert-butoxycarbonyl (Boc) group is selectively removed under acidic conditions (e.g., TFA) |
| Organic Synthesis | Multifunctional amino-based linker for constructing PROTAC molecules, antibody–drug conjugate (ADC) linkers, and targeted probes | Used as a spacer to connect the target protein ligand and the E3 ligase ligand (in PROTACs) or to link the antibody and cytotoxic payload (in ADCs); typically incorporated into the molecular scaffold via amidation, urea formation, or thiourea formation |
Physical and chemical properties of 51857-17-1
Acidity coefficient |
12.93±0.46(Predicted) |
|---|---|
Boiling Point |
325.3±25.0 °C at 760 mmHg |
BRN |
2089264 |
Density |
1.0±0.1 g/cm3 |
Exact Mass |
216.183777 |
Flash Point |
150.5±23.2 °C |
Index of Refraction |
1.460 |
LogP |
1.82 |
Melting Point |
89 to 91°C°C |
Molecular Formula |
C11H24N2O2 |
Molecular Weight |
216.320 |
PSA |
64.35000 |
Sensitivity |
Air Sensitive |
Solubility |
Soluble in dichloromethane and ethyl acetate. |
Storage condition |
Keep in dark place,Inert atmosphere,2-8°C |
Vapour Pressure |
0.0±0.7 mmHg at 25°C |
Spectrums of 51857-17-1
1.The NMR spectrum displayed on the page is a pre-sale reference spectrum and may differ from that of the actual received batch.
2.The accompanying documentation will include the NMR spectrum and purity analysis data for the shipped batch.
Retrosynthesis analysis of 51857-17-1
Cas:16644-54-5
Cas:85535-56-4
Cas:6404-29-1
Q&A for CAS 51857-17-1
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Download SDS of 51857-17-1
Pictograms |
 |
|---|---|
Signal Word |
Danger |
Hazard Statements |
H314 Causes severe skin burns and eye damage |
Safety Data Sheet |
Download COA of 51857-17-1
Operate under the ISO 9001 system
