Pyrithiamine Hydrobromide
| Purity | Grade | Package | Stock | Price | Quantity |
|---|---|---|---|---|---|
| 98% | RG | 1MG | In Stock | 164 USD | |
| 98% | RG | 5MG | In Stock | 487 USD | |
| 98% | RG | 25MG | In Stock | 1364 USD | |
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Applications of 534-64-5
Pyrithiamine is primarily utilized in scientific research, particularly in neurobiology and pharmacology. Its applications include:
- Modeling Thiamine Deficiency: Used extensively in animal studies to simulate the effects of thiamine deficiency.
- Investigating Neurological Disorders: Helps researchers understand the biochemical pathways affected by thiamine deficiency and related neurological conditions.
- Antimicrobial Research: Explored for its potential use against certain bacterial and fungal infections due to its ability to interact with riboswitches.
Biological Activity of 534-64-5
Pyrithiamine exhibits notable biological activity primarily through its role as an inhibitor of thiamine-dependent enzymes. Studies have indicated that it leads to reductions in neurotransmitter levels such as glutamate and aspartate in the brain, which are critical for normal neuronal function. The compound has been used to model Wernicke's encephalopathy in rats, demonstrating similar neuropathological changes observed in humans suffering from thiamine deficiency. Additionally, pyrithiamine has antimicrobial properties, interacting with riboswitches in bacteria and fungi, thereby inhibiting their growth.
Safety Information of 534-64-5
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Bulk Packaging Price Explanation of 534-64-5
Please email your required order quantity and detailed technical specifications to sales@.
Our sales team will promptly prepare an accurate quotation for your bulk order and provide a comprehensive pricing proposal.
Purchase Instructions of 534-64-5
All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.
These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.
Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.
New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.
