structure of 54-36-4

2-Methyl-1,2-Di(Pyridin-3-Yl)Propan-1-One

CAS No.: 54-36-4 Brand: MolBest
M. Ft.: C14H14N2O Cat. No: G1201400
M. Wt.: 226.27 MDL: No record
Storage: Store under inert gas.
Purity Grade Package Stock Price Quantity
99% RG 100MG In Stock 17 USD
99% RG 250MG In Stock 21 USD
99% RG 1G In Stock 72 USD
99% RG 5G In Stock 353 USD
99% RG 25G In Stock 2642 USD
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Applications of 54-36-4

Metyrapone has several clinical applications:

  • Diagnosis of Adrenal Insufficiency: It is used as a diagnostic tool to assess adrenal function by measuring plasma cortisol and ACTH levels after administration.
  • Management of Cushing's Syndrome: Metyrapone serves as a treatment option for controlling excessive cortisol production in patients with Cushing's syndrome, particularly when surgery is not feasible.
  • Research

Biological Activity of 54-36-4

The biological activity of metyrapone is significant in both clinical and research settings. In patients with Cushing's syndrome, it effectively lowers cortisol levels, alleviating symptoms associated with hypercortisolism. Its pharmacological effects include:

  • Inhibition of Cortisol Production: Metyrapone inhibits the final step in cortisol synthesis, leading to decreased plasma cortisol levels.
  • Stimulation of ACTH Secretion: The reduction in cortisol removes negative feedback on the pituitary gland, resulting in increased ACTH secretion.
  • Effects on Emotional Memory: Research indicates that metyrapone may impair retrieval of emotionally charged memories without affecting neutral memories, suggesting potential applications in treating conditions like post-traumatic stress disorder.

NMR spectrum of 54-36-4

Physical sample testing spectrum (NMR) of 54-36-4

Safety Information of 54-36-4

Pictograms

Signal Word

Warning

Hazard Statements

H302 Harmful if swallowed
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation

Safety Data Sheet

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Bulk Packaging Price Explanation of 54-36-4

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Purchase Instructions of 54-36-4

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