structure of 550378-39-7

(S)-1-Cbz-3-Aminopyrrolidine Hydrochloride(CAS 550378-39-7)

CAS No.: 550378-39-7 Brand: MolBest
M. Ft.: C12H16l2O2·HCl Cat. No: G6071230
M. Wt.: 256.73 MDL: No record
Storage: Store in a cool,dry area. Use: For laboratory research use only
HS CODE: 2933990090
Purity Grade Package Stock Price Quantity
95%
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RG 250MG In Stock 6 USD
95%
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RG 1G In Stock 8 USD
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RG 5G In Stock 26 USD
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RG 25G In Stock 199 USD
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RG 100G In Stock 775 USD
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Applications of 550378-39-7

Industry Application Process
Pharmaceutical Intermediates Key chiral building block for synthesizing antiviral drugs (e.g., HCV NS3/4A protease inhibitors) Used as a chiral amine source in coupling reactions; target molecular core structure is constructed via deprotection, acylation, and related steps
Pharmaceutical Intermediates Pyrrolidine ring precursor for synthesizing selective 5-HT2C receptor agonists (e.g., lorcaserin analogues) used as anti-obesity agents (S)-configured pyrrolidine scaffold is introduced via chirally induced cyclization or asymmetric reductive amination
Pharmaceutical Intermediates Preparation of kinase inhibitors containing a 3-aminopyrrolidine motif (e.g., ROCK and ALK inhibitors) After Cbz deprotection, undergoes condensation with carboxylic acid derivatives or participates in SNAr reactions to form C–N bonds

Physical and chemical properties of 550378-39-7

Boiling Point

103 °C10 mm Hg(lit.)

Density

1.208 g/mL at 25 °C(lit.)

Exact Mass

256.097870

Flash Point

220 °F

H Bond Acceptors

2

H Bond Donors

1

Index of Refraction

n20/D 1.551(lit.)

LogP

2.79640

Molecular Formula

C12H17ClN2O2

Molecular Weight

256.729

PSA

55.56000

Storage condition

Inert atmosphere,Room Temperature

Water Solubility

Soluble in water

Retrosynthesis analysis of 550378-39-7

  • Route#1

    Cas:122536-74-7
    Cas:550378-39-7
  • Route#2

    Cas:185057-49-2
    Cas:550378-39-7
  • Route#3

    Cas:550378-39-7

Q&A for CAS 550378-39-7

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Download SDS of 550378-39-7

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Signal Word

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Hazard Statements

H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation

Safety Data Sheet

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Operate under the ISO 9001 system