structure of 56-57-5

4-Nitroquinoline N-Oxide

CAS No.: 56-57-5 Brand: MolBest
M. Ft.: C9H6N2O3 Cat. No: G9541605
M. Wt.: 190.16 MDL: MFCD00006738
Storage: -20°C
Purity Grade Package Stock Price Quantity
95% RG 250MG In Stock 4 USD
95% RG 5G In Stock 40 USD
95% RG 25G In Stock 439 USD
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Applications of 56-57-5

4-Nitroquinoline N-oxide has several applications in scientific research:

  • Mutagenesis Studies: It is frequently used as a mutagen in genetic screens to study DNA damage and repair mechanisms.
  • Cancer Research: The compound serves as a model for investigating carcinogenic processes and evaluating potential chemotherapeutic agents.
  • Toxicology: It aids in understanding the toxicological effects of environmental pollutants on cellular systems.

Biological Activity of 56-57-5

The biological activity of 4-nitroquinoline N-oxide is primarily characterized by its mutagenic and carcinogenic effects. It induces mutations in various organisms, including bacteria and eukaryotic cells, through the formation of bulky purine adducts. The compound exhibits a significant preference for guanine over adenine when forming these adducts, leading to a high frequency of mutations in guanine residues. Additionally, it has been shown to generate reactive oxygen species, contributing further to its genotoxicity.

NMR spectrum of 56-57-5

Physical sample testing spectrum (NMR) of 56-57-5

Safety Information of 56-57-5

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Danger

Hazard Statements

H350 May cause cancer

Safety Data Sheet

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Purchase Instructions of 56-57-5

All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

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