2-Ethoxy-5-fluoro-1H-pyrimidin-4-one

The biological activity of 2-Ethoxy-5-fluorouracil is primarily attributed to its role as an antimetabolite. It acts by inhibiting thymidylate synthase, leading to disrupted DNA and RNA synthesis. This inhibition results in cell death, making it effective against rapidly dividing cancer cells. Additionally, it can lead to the formation of fraudulent RNA when incorporated in place of uridine triphosphate, further interfering with protein synthesis.

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