structure of 58-72-0

Triphenylethylene

CAS No.: 58-72-0 Brand: MolBest
M. Ft.: C20H16 Cat. No: G1654896
M. Wt.: 256.34 MDL: MFCD00004765
Storage: Store in a cool,dry area.
Purity Grade Package Stock Price Quantity
98% RG 1G In Stock 4 USD
98% RG 5G In Stock 13 USD
98% RG 25G In Stock 46 USD
98% RG 100G In Stock 173 USD
98% RG 500G In Stock 665 USD
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Applications of 58-72-0

TamoxifenTriphenyl derivativeModerateBreast cancer treatmentClomifeneTriphenyl derivativeModerateOvulation inductionRaloxifeneBenzothiophene derivativeSelectiveOsteoporosis treatmentEthamoxytriphetolTriphenylethanol derivativeWeakAntiestrogen researchToremifeneTriphenyl derivativeModerateBreast cancer treatment

Biological Activity of 58-72-0

Triphenylethylene exhibits weak estrogenic activity, with its affinity for the rat estrogen receptor being approximately 0.002% relative to estradiol. This compound acts as a selective estrogen receptor modulator (SERM), influencing various biological processes such as:

  • Bone Density Maintenance: Some derivatives of triphenylethylene have been shown to prevent bone loss in ovariectomized rats, indicating potential applications in osteoporosis treatment.
  • Antitumor Activity: Certain derivatives, like FC1271a, have demonstrated the ability to inhibit tumor growth in breast cancer models while exhibiting low uterotropic activity.
  • Cholesterol Regulation: Research indicates that triphenylethylene derivatives can help maintain cholesterol levels, providing additional therapeutic benefits.

NMR spectrum of 58-72-0

Physical sample testing spectrum (NMR) of 58-72-0

Safety Information of 58-72-0

Pictograms

Signal Word

Warning

Hazard Statements

H302 Harmful if swallowed
H319 Causes serious eye irritation
H400 Very toxic to aquatic life
H410 Very toxic to aquatic life with long lasting effects

Safety Data Sheet

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Bulk Packaging Price Explanation of 58-72-0

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Purchase Instructions of 58-72-0

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