Calcium Folinate Pentahydrate(CAS 6035-45-6)
| Purity | Grade | Package | Stock | Price | Quantity |
| 98% | RG | 250MG | In Stock | 2 USD
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| 98% | RG | 1G | In Stock | 3 USD
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| 98% | RG | 5G | In Stock | 13 USD
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| 98% | RG | 25G | In Stock | 39 USD
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| 98% | RG | 100G | In Stock | 143 USD
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| 98% | RG | 500G | In Stock | 1306 USD
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| Bulk Packaging | 25KG | substantially lower unit cost than small-pack SKUs. Contact us for a fast quotation. | |||
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Applications of 6035-45-6
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Antidote for overdose or toxicity of folate antagonists (e.g., methotrexate) | Administered intravenously or orally to supply biologically active tetrahydrofolate, bypassing inhibited dihydrofolate reductase and restoring purine and pyrimidine synthesis |
| Pharmaceuticals | Adjunct to enhance the antitumor efficacy of 5-fluorouracil (5-FU) | Co-administered intravenously with 5-FU; calcium leucovorin stabilizes and potentiates the binding of 5-FU metabolite FdUMP to thymidylate synthase, prolonging enzyme inhibition |
| Pharmaceuticals | Treatment of folate-deficiency megaloblastic anemia (particularly in cases of malabsorption or metabolic impairment) | Administered orally or intramuscularly to directly supply physiologically active L-leucovorin (6S-leucovorin calcium), eliminating the need for conversion by dihydrofolate reductase |
Physical and chemical properties of 6035-45-6
H Bond Acceptors |
11 |
|---|---|
H Bond Donors |
5 |
LogP |
log Kow = -4.45 /Estimated/ |
Melting Point |
245 °C (decomp) |
Molecular Formula |
C20H31CaN7O12 |
Molecular Weight |
601.58 |
pH |
pH of saturated solution in water = 2.8-3.0. |
PSA |
427.76000 |
Specific rotation |
D21 +14.9° (c = 1 in water) |
Stability |
Leucovorin calcium injection, powder for injection, and tablets should be stored at 15-30 °C and protected from light. /Leucovorin calcium/ |
Storage condition |
-20℃ |
Vapour Pressure |
2.3X10-21 mm Hg at 25 °C at 25 °C /Estimated/ |
Spectrums of 6035-45-6
1.The NMR spectrum displayed on the page is a pre-sale reference spectrum and may differ from that of the actual received batch.
2.The accompanying documentation will include the NMR spectrum and purity analysis data for the shipped batch.
Retrosynthesis analysis of 6035-45-6
Cas:135-16-0
Cas:93-61-8
Q&A for CAS 6035-45-6
1. How can I verify product quality?
Every batch of our Chemical Reagents is tested to meet ISO 9001 standards. We provide COA & NMR & SDS Provided with each shipment. Batch COA available for verification, and third-party retesting is supported. A full refund is offered if our data is incorrect.
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If your Lab Grade Chemical Reagents do not match the Batch COA available, we will issue a replacement or a full refund upon verification.
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Hazardous products are labeled and packaged following international regulations. We provide SDS Provided with all hazardous shipments to ensure safe and compliant transport.
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Yes, samples are available for selected Lab Grade products. Please submit a request to confirm availability and specifications.
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Yes. We support customization of Lab Grade purity, packaging size, and special testing requirements. Share your needs and we’ll provide a tailored solution.
10. Is the COA consistent with the shipped batch?
Yes. Batch COA available matches the actual shipment. COAs shown online are for reference or from previous batches.
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Yes. We offer Lab Supplier services for stable batch consistency, pricing agreements, and safety stock for long-term customers to ensure uninterrupted supply.
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Download SDS of 6035-45-6
Pictograms |
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|---|---|
Signal Word |
Danger |
Hazard Statements |
H315 Causes skin irritation H317 May cause an allergic skin reaction H319 Causes serious eye irritation H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled H335 May cause respiratory irritation |
Safety Data Sheet |
Download COA of 6035-45-6
Operate under the ISO 9001 system
