6-Mercaptopurine Monohydrate

6-Mercaptopurine monohydrate has several key applications:

• Cancer Treatment: Primarily used in treating acute lymphoblastic leukemia.
• Immunosuppressive Therapy: Employed in organ transplantation to prevent rejection.
• Autoimmune Disorders: It can be used off-label for conditions like Crohn's disease and ulcerative colitis .

6-Mercaptopurine monohydrate exhibits significant biological activity as follows:

• Antineoplastic Properties: It disrupts DNA and RNA synthesis by inhibiting purine nucleotide synthesis, particularly during the S phase of the cell cycle. This action leads to the death of rapidly proliferating cells, including malignant ones .
• Immunomodulatory Effects: The compound also acts as an immunosuppressant by inhibiting pathways involved in nucleic acid biosynthesis, which prevents the proliferation of immune cells .
• Side Effects: Common adverse reactions include myelosuppression, nausea, vomiting, diarrhea, and potential liver toxicity .

Please email your required order quantity and detailed technical specifications to sales@.
Our sales team will promptly prepare an accurate quotation for your bulk order and provide a comprehensive pricing proposal.

All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.