structure of 622405-78-1

2,5-Dioxopyrrolidin-1-Yl2,5,8,11-Tetraoxatetradecan-14-Oate

CAS No.: 622405-78-1 Brand: MolBest
M. Ft.: C14H23NO8 Cat. No: G8442166
M. Wt.: 333.33 MDL: No record
Storage: -20°C
Purity Grade Package Stock Price Quantity
97% RG 250MG In Stock 13 USD
97% RG 5G In Stock 185 USD
97% RG 25G In Stock 1584 USD
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Applications of 622405-78-1

m-PEG4-NHS ester has a wide range of applications, including:

  • Protein Labeling: Used for attaching fluorescent dyes or biotin to proteins for detection and purification.
  • Drug Development: Serves as a linker in the synthesis of bioconjugates for targeted drug delivery.
  • Surface Modification: Enhances the properties of surfaces in biomedical devices by creating a hydrophilic layer that reduces protein adsorption.
  • PROTACs Synthesis: Acts as a linker in the development of PROTACs, facilitating targeted degradation of specific proteins.

Biological Activity of 622405-78-1

m-PEG4-NHS ester exhibits significant biological activity due to its ability to selectively modify proteins and peptides. By attaching m-PEG4-NHS ester to biomolecules, researchers can enhance solubility, reduce immunogenicity, and improve pharmacokinetic properties. Its application in drug delivery systems and therapeutic agents has been widely studied, particularly in the development of targeted therapies such as PROTACs (proteolysis-targeting chimeras).

NMR spectrum of 622405-78-1

Physical sample testing spectrum (NMR) of 622405-78-1

Safety Information of 622405-78-1

Pictograms

Signal Word

Warning

Hazard Statements

H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation

Safety Data Sheet

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Purchase Instructions of 622405-78-1

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