structure of 62327-21-3

Tert-Butyl O,O-Dimethylphosphonoacetate(CAS 62327-21-3)

CAS No.: 62327-21-3 Brand: MolBest
M. Ft.: C8H17O5P Cat. No: G7043900
M. Wt.: 224.19 MDL: MFCD00042939
Storage: Store in a cool,dry area. Use: For laboratory research use only
Purity Grade Package Stock Price Quantity
95%
Documents:COANMRGCMSSDS
RG 25G In Stock 9 USD
95%
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RG 500G In Stock 138 USD
98%
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RG 5G In Stock 4 USD
98%
Documents:COANMRGCMSSDS
RG 25G In Stock 11 USD
98%
Documents:COANMRGCMSSDS
RG 100G In Stock 37 USD
98%
Documents:COANMRGCMSSDS
RG 500G In Stock 113 USD
98%
Documents:COANMRGCMSSDS
RG 2.5KG In Stock 822 USD
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Applications of 62327-21-3

Industry Application Process
Pharmaceutical Industry Key intermediate for antiviral drugs (e.g., tenofovir, tenofovir alafenamide fumarate) Constructs the phosphonyl group via the Arbuzov or Michaelis–Arbuzov reaction; serves as a phosphonylating reagent to introduce the phosphonic acid moiety
Pharmaceutical Industry Synthesis of nucleoside (nucleotide) analogues Undergoes nucleophilic substitution or condensation with purine or pyrimidine derivatives to form carbon–phosphorus bonds
Agrochemical Industry Synthesis of organophosphorus herbicides and insecticides Serves as a phosphonyl-containing acetate structural unit, participating in condensation or addition reactions to synthesize target agrochemical molecules
Fine Chemicals R&D of active pharmaceutical ingredients (APIs) and advanced intermediates Leverages its dual functional groups—phosphonyl and ester—for selective hydrolysis, reduction, or coupling reactions
Biochemistry Synthesis of nucleotide analogues Mimics natural nucleotide structures to synthesize biologically active phosphonate ester derivatives

Physical and chemical properties of 62327-21-3

Boiling Point

86-87ºC (0.02 mmHg)

BRN

4861886

Density

1.131

Exact Mass

224.08100

Flash Point

110ºC

Index of Refraction

1.434

LogP

1.81400

Molecular Formula

C8H17O5P

Molecular Weight

224.19100

PSA

71.64000

Storage condition

under inert gas (nitrogen or Argon) at 2-8°C

Spectrums of 62327-21-3

Attention:
1.The NMR spectrum displayed on the page is a pre-sale reference spectrum and may differ from that of the actual received batch.
2.The accompanying documentation will include the NMR spectrum and purity analysis data for the shipped batch.
Physical sample testing spectrum (NMR) of 62327-21-3

Retrosynthesis analysis of 62327-21-3

Q&A for CAS 62327-21-3

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Download SDS of 62327-21-3

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Signal Word

Warning

Hazard Statements

H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation

Safety Data Sheet

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Operate under the ISO 9001 system