structure of 624-95-3

3,3-Dimethyl-1-Butanol

CAS No.: 624-95-3 Brand: MolBest
M. Ft.: C6H14O Cat. No: G5366940
M. Wt.: 102.17 MDL: MFCD00002928
Storage: Store in a cool,dry area.
Purity Grade Package Stock Price Quantity
97% RG 25ML In Stock 7 USD
97% RG 100ML In Stock 24 USD
97% RG 500ML In Stock 114 USD
97% RG 2.5L In Stock 893 USD
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Applications of 624-95-3

3,3-Dimethyl-1-butanol has several applications:

  • Pharmaceutical intermediate: It is used as an organic building block for the synthesis of various pharmaceutical compounds.
  • Potential therapeutic agent: Its ability to ameliorate collagen-induced arthritis suggests potential applications in treating rheumatoid arthritis and other inflammatory conditions.
  • Cardiovascular health: Its inhibitory effect on TMAO production may have applications in preventing or treating cardiovascular diseases.
  • Research tool: The compound is used in studies investigating gut microbiome interactions and their effects on host health.

Biological Activity of 624-95-3

3,3-Dimethyl-1-butanol exhibits several biological activities:

  • Inhibition of microbial trimethylamine (TMA) formation: It reduces plasma trimethylamine N-oxide (TMAO) levels after choline or carnitine supplementation in mice and human feces.
  • Atherosclerosis prevention: The compound inhibits choline-enhanced endogenous macrophage foam cell formation and atherosclerotic lesion development in mice without altering circulating cholesterol levels.
  • Gut microbiome modulation: While choline supplementation increases the proportions of Clostridiales in the gut, 3,3-Dimethyl-1-butanol induces a decrease in this bacterial taxon.
  • Amelioration of collagen-induced arthritis (CIA): Treatment with 3,3-Dimethyl-1-butanol significantly reduces arthritis severity in mice models.
  • Anti-inflammatory effects: The compound and its metabolite, 3,3-dimethyl-1-butyric acid, reduce proinflammatory cytokines in CIA mice.

NMR spectrum of 624-95-3

Physical sample testing spectrum (NMR) of 624-95-3

Safety Information of 624-95-3

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Signal Word

Warning

Hazard Statements

H226 Flammable liquid and vapor

Safety Data Sheet

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Purchase Instructions of 624-95-3

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