structure of 635-39-2

Guanine Hydrochloride

CAS No.: 635-39-2 Brand: MolBest
M. Ft.: C5H6ClN5O Cat. No: G7953527
M. Wt.: 187.59 MDL: MFCD00213670
Storage: 2-8°C
Purity Grade Package Stock Price Quantity
98% RG 5G In Stock 3 USD
98% RG 25G In Stock 9 USD
98% RG 500G In Stock 185 USD
98% RG 2.5KG In Stock 888 USD
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Applications of 635-39-2

Guanidine hydrochloride has diverse applications across various fields:

  • Biochemistry: Utilized extensively for protein denaturation studies and refolding experiments.
  • Pharmaceuticals: Employed in the treatment of neuromuscular disorders.
  • Organic Synthesis: Acts as a catalyst in various organic reactions, enhancing reaction rates and yields.
  • Laboratory Reagent: Used as a chaotropic agent in nucleic acid isolation protocols.

Biological Activity of 635-39-2

Guanidine hydrochloride exhibits several biological activities:

  • Protein Denaturation: Its primary application in biochemistry is as a denaturant for proteins, which aids in studying protein folding and stability. It disrupts non-covalent interactions within proteins, leading to loss of structure.
  • Enzyme Modulation: At low concentrations, guanidine hydrochloride can stimulate the activity of certain enzymes, such as tryptophan synthase. It acts both as a cation activator and a chaotropic agent, influencing enzyme conformations and reaction pathways.
  • Therapeutic Uses: In medicine, guanidine hydrochloride is used to treat muscle weakness associated with Eaton-Lambert syndrome by enhancing acetylcholine release at neuromuscular junctions.

NMR spectrum of 635-39-2

Physical sample testing spectrum (NMR) of 635-39-2

Safety Information of 635-39-2

Pictograms

Signal Word

Warning

Hazard Statements

H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation

Safety Data Sheet

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Purchase Instructions of 635-39-2

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