structure of 641571-10-0

Nilotinib(CAS 641571-10-0)

CAS No.: 641571-10-0 Brand: MolBest
M. Ft.: C28H22F3N7O Cat. No: G3579934
M. Wt.: 529.52 MDL: MFCD09833716
Storage: -20°C, 3 years; 2-8°C, 2 years. Use: For laboratory research use only
Purity Grade Package Stock Price Quantity
98%
Documents:COANMRLCMSSDS
RG 100MG In Stock 9 USD
98%
Documents:COANMRLCMSSDS
RG 250MG In Stock 24 USD
98%
Documents:COANMRLCMSSDS
RG 1G In Stock 47 USD
98%
Documents:COANMRLCMSSDS
RG 5G In Stock 187 USD
98%
Documents:COANMRLCMSSDS
RG 25G In Stock 907 USD
99%
Documents:COANMRLCMSSDS
RG 1G In Stock 60 USD
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Applications of 641571-10-0

Nilotinib is primarily utilized for treating Philadelphia chromosome-positive chronic myeloid leukemia (CML). It is indicated for:

  • First-line treatment in chronic phase CML.
  • Treatment for patients with CML who exhibit resistance or intolerance to imatinib.

Additionally, nilotinib has been explored for use in other malignancies involving similar tyrosine kinase pathways.

Physical and chemical properties of 641571-10-0

Density

1.4±0.1 g/cm3

Exact Mass

529.183777

Index of Refraction

1.650

LogP

log Kow = 5.01 (est)

Melting Point

231-233 °C

Molecular Formula

C28H22F3N7O

Molecular Weight

529.516

PSA

97.62000

Solubility

2.01e-03 g/L

Stability

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.

Storage condition

-20°C Freezer

Vapour density

2.06X10-18 mm Hg at 25 °C (est)

Spectrums of 641571-10-0

Attention:
1.The NMR spectrum displayed on the page is a pre-sale reference spectrum and may differ from that of the actual received batch.
2.The accompanying documentation will include the NMR spectrum and purity analysis data for the shipped batch.
Physical sample testing spectrum (NMR) of 641571-10-0

Retrosynthesis analysis of 641571-10-0

  • Route#1

    Cas:1205540-16-4
    Cas:641571-10-0
  • Route#2

    Cas:915711-42-1
    Cas:641571-10-0
  • Route#3

    Cas:926922-18-1
    Cas:641571-10-0

Q&A for CAS 641571-10-0

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Download SDS of 641571-10-0

Pictograms

Signal Word

Danger

Hazard Statements

H361 Suspected of damaging fertility or the unborn child
H361fd Suspected of damaging fertility; Suspected of damaging the unborn child
H372 Causes damage to organs through prolonged or repeated exposure
H373 May causes damage to organs through prolonged or repeated exposure
H400 Very toxic to aquatic life
H410 Very toxic to aquatic life with long lasting effects
H413 May cause long lasting harmful effects to aquatic life

Safety Data Sheet

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Operate under the ISO 9001 system