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structure of 65277-42-1

Ketoconazole(CAS 65277-42-1)

CAS No.: 65277-42-1 Brand: MolBest
M. Ft.: C26H28Cl2N4O4 Cat. No: G5111188
M. Wt.: 531.43 MDL: MFCD00058579
Storage: 2-8°C Use: For laboratory research use only
HS CODE: 2933990090 UN No.: UN 2811 6.1 /PG III
Purity Grade Package Stock Price Quantity
98%
Documents:COANMRHPLCSDS
RG 1G In Stock 2 USD
98%
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RG 5G In Stock 4 USD
98%
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RG 25G In Stock 9 USD
98%
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RG 100G In Stock 27 USD
98%
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RG 500G In Stock 93 USD
98%
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RG 2.5KG In Stock 846 USD
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Applications of 65277-42-1

Industry Application Process
Pharmaceutical Industry Antifungal agent for treating dermatophytosis, candidiasis, and other fungal skin infections Manufactured via chemical synthesis using ketones and amines as primary raw materials, followed by condensation, cyclization, and related reaction steps
Pharmaceutical Industry Active ingredient in topical formulations, such as lotions, creams, and ointments Formulated into various dosage forms by blending ketoconazole with excipients and processing via emulsification and homogenization
Pharmaceutical Industry Active ingredient in oral formulations for systemic fungal infection treatment Processed into tablets or capsules via granulation, compression, and related unit operations

Physical and chemical properties of 65277-42-1

Acidity coefficient

pKa 3.25/6.22(H2O,t =25,I=0.025) (Uncertain)

Boiling Point

753.37 °C. @ 760.00 mm Hg (est)

Decomposition

When heated to decomposition it emits toxic fumes of /hydrogen chloride and nitrogen oxides/.

Density

1.4±0.1 g/cm3

Exact Mass

530.148743

Flash Point

409.4±32.9 °C

Index of Refraction

1.642

LogP

4.35

Melting Point

148-152 °C

Merck

14,5302

Molecular Formula

C26H28Cl2N4O4

Molecular Weight

531.431

optical activity

[α]20/D -1 to 1°, c = 4 in methanol

PSA

69.06000

Solubility

Solubility in water: none

Stability

Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.

Storage condition

2-8°C

Vapour Pressure

Vapor pressure, Pa at 25 °C: (negligible)

Water Solubility

Soluble in DMSO, ethanol, chloroform, water, and methanol.

Spectrums of 65277-42-1

Attention:
1.The NMR spectrum displayed on the page is a pre-sale reference spectrum and may differ from that of the actual received batch.
2.The accompanying documentation will include the NMR spectrum and purity analysis data for the shipped batch.
Physical sample testing spectrum (NMR) of 65277-42-1

Retrosynthesis analysis of 65277-42-1


Q&A for CAS 65277-42-1

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Download SDS of 65277-42-1

Pictograms

Signal Word

Danger

Hazard Statements

H301 Toxic if swallowed
H360 May damage fertility or the unborn child
H360F May damage fertility
H373 May causes damage to organs through prolonged or repeated exposure
H400 Very toxic to aquatic life
H410 Very toxic to aquatic life with long lasting effects

Safety Data Sheet

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