structure of 657-24-9

Metformin(CAS 657-24-9)

CAS No.: 657-24-9 Brand: MolBest
M. Ft.: C4H11N5 Cat. No: G7250298
M. Wt.: 129.16 MDL: MFCD00242652
Storage: Store in a cool,dry area. Use: For laboratory research use only
Purity Grade Package Stock Price Quantity
97%
Documents:COANMRHPLCSDS
RG 250MG In Stock 4 USD
97%
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RG 1G In Stock 10 USD
97%
Documents:COANMRHPLCSDS
RG 5G In Stock 40 USD
97%
Documents:COANMRHPLCSDS
RG 25G In Stock 129 USD
97%
Documents:COANMRHPLCSDS
RG 100G In Stock 513 USD
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Applications of 657-24-9

Industry Application Process
Pharmaceutical Industry First-line oral antihyperglycemic agent for type 2 diabetes mellitus As an active pharmaceutical ingredient (API), formulated into tablets, capsules, or extended-release tablets via oral solid dosage manufacturing processes to improve glycemic control in patients with type 2 diabetes.
Pharmaceutical Industry Treatment of polycystic ovary syndrome (PCOS) Used off-label or per clinical guidelines based on its insulin-sensitizing mechanism to regulate menstrual cycles and support ovulation in PCOS patients.
Pharmaceutical Industry Adjunctive therapy for gestational diabetes mellitus Administered under specific medical supervision for glycemic control during pregnancy, as an alternative or supplement to insulin therapy.
Scientific Research Studies on anti-aging and longevity mechanisms Employed in model organisms (e.g., nematodes, mice) to investigate its potential to delay aging, extend lifespan, and prevent age-related diseases—primarily through AMPK pathway activation.
Scientific Research Investigation of antineoplastic activity Used as a research reagent in cellular and preclinical studies to evaluate its inhibitory effects on proliferation of multiple cancer cell lines (e.g., breast, colorectal) via mitochondrial complex I inhibition and glucose-lowering mechanisms.
Scientific Research Neuroprotective effect studies Applied in neurodegenerative disease research to assess its potential therapeutic effects in Alzheimer’s and Parkinson’s diseases—through modulation of energy metabolism and attenuation of inflammatory responses.
Chemical Industry Organic synthesis intermediate As a guanidine derivative, used to synthesize other heterocyclic compounds or serve as a nitrogen source in condensation reactions within fine chemical synthesis processes.
Environmental Analysis Reference standard for analytical testing Used as a certified reference material or analytical standard in pharmaceutical analysis and environmental water testing to develop and validate analytical methods such as HPLC and MS.

Physical and chemical properties of 657-24-9

Acidity coefficient

pKa 2.8(H2O,t =32) (Uncertain)

Appearance of Characters

Solid,White to Light Brown

Boiling Point

224.1ºC at 760 mmHg

Decomposition

When heated to decomposition it emits toxic fumes of /nitric oxides/.

Density

1.0743

Exact Mass

129.101440

Flash Point

58.1±22.6 °C

H Bond Acceptors

2

H Bond Donors

4

Index of Refraction

1.576

LogP

log Kow = -2.64 at 25 °C (est)

Melting Point

223 - 226 °C

Molecular Formula

C4H11N5

Molecular Weight

129.164

PSA

88.99000

Stability

Stable under recommended storage conditions. /Metformin hydrochloride/

Storage condition

Keep in dark place,Inert atmosphere,Room temperature

Vapour Pressure

7.58X10-5 mm Hg at 25 °C (est)

Water Solubility

Acetonitrile (Slightly), Aqueous Acid (Slightly), Dichloromethane (Slightly), DM

Spectrums of 657-24-9

Attention:
1.The NMR spectrum displayed on the page is a pre-sale reference spectrum and may differ from that of the actual received batch.
2.The accompanying documentation will include the NMR spectrum and purity analysis data for the shipped batch.
Physical sample testing spectrum (NMR) of 657-24-9

Retrosynthesis analysis of 657-24-9


Q&A for CAS 657-24-9

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Download SDS of 657-24-9

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Signal Word

Warning

Hazard Statements

H302 Harmful if swallowed

Safety Data Sheet

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