structure of 66427-86-9

2-Chloro-11-Methyl-5H-Benzo[E]Pyrimido[5,4-B][1,4]Diazepin-6(11H)-One(CAS 66427-86-9)

CAS No.: 66427-86-9 Brand: MolBest
M. Ft.: C12H9ClN4O Cat. No: G2751242
M. Wt.: 260.68 MDL: MFCD19703985
Storage: Store in a cool,dry area. Use: For laboratory research use only
Purity Grade Package Stock Price Quantity
98%
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RG 100MG In Stock 98 USD
98%
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RG 250MG In Stock 164 USD
98%
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RG 1G In Stock 329 USD
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Applications of 66427-86-9

The primary application of 2-Chloro-11-methyl-5H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6(11H)-one lies in medicinal chemistry as a potential therapeutic agent targeting specific kinases involved in cancer progression. Its selectivity for BMK1 suggests it may be developed into a targeted therapy for cancers where this kinase plays a critical role. Additionally, its unique scaffold could lead to the discovery of new inhibitors for other related kinases.

Physical and chemical properties of 66427-86-9

Boiling Point

399.7ºC at 760 mmHg

Density

1.403g/cm3

Exact Mass

260.04600

Flash Point

195.5ºC

Index of Refraction

1.636

LogP

2.02540

Molecular Formula

C12H9ClN4O

Molecular Weight

260.67900

PSA

63.57000

Retrosynthesis analysis of 66427-86-9

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Hazard Statements

H302 Harmful if swallowed

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