structure of 673-49-4

N-Omega-Acetylhistamine

CAS No.: 673-49-4 Brand: MolBest
M. Ft.: C7H11N3O Cat. No: G3495214
M. Wt.: 153.18 MDL: No record
Storage: Store in a cool,dry area.
Purity Grade Package Stock Price Quantity
98% RG 100MG In Stock 18 USD
98% RG 250MG In Stock 28 USD
98% RG 1G In Stock 69 USD
98% RG 5G In Stock 461 USD
98% RG 25G In Stock 2214 USD
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Applications of 673-49-4

N-Acetylhistamine has several applications in research and industry:

  • Biomarker: It can be used as a potential biomarker of histidine metabolism for anaphylactoid reactions.
  • Pharmaceutical research: N-Acetylhistamine is investigated for its potential therapeutic effects, particularly in the context of allergic reactions and inflammation.
  • Chemical synthesis: It serves as a precursor in the synthesis of other histamine derivatives and imidazole compounds.
  • Biochemical studies: N-Acetylhistamine is utilized as a research tool in studies related to histamine metabolism and neurotransmission.

Biological Activity of 673-49-4

N-Acetylhistamine exhibits several biological activities:

  • Histamine metabolism: It is a metabolite of histamine, formed through acetylation.
  • Enzyme inhibition: N-Acetylhistamine selectively inhibits sweet-almond beta-glucosidase (Ki = 0.035 mM) and human glutaminyl cyclase (IC50 = 17 µM).
  • Neurotransmission: As a histamine derivative, it may influence neurotransmission processes.
  • Anaphylaxis: Unlike histamine, N-Acetylhistamine has no effect on eosinophil activity and has been used as a negative control for histamine-mediated anaphylaxis.

NMR spectrum of 673-49-4

Physical sample testing spectrum (NMR) of 673-49-4

Safety Information of 673-49-4

Pictograms

Signal Word

Warning

Hazard Statements

H302 Harmful if swallowed
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation

Safety Data Sheet

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Purchase Instructions of 673-49-4

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